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Merck
CN

161M-1

CD61 (2f2) Mouse Monoclonal Antibody

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关于此项目

NACRES:
NA.41
UNSPSC Code:
12352203
Conjugate:
unconjugated
Clone:
2f2, monoclonal
Application:
IHC (p)
Citations:
7
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biological source

mouse

Quality Level

conjugate

unconjugated

antibody form

culture supernatant

antibody product type

primary antibodies

clone

2f2, monoclonal

description

For In Vitro Diagnostic Use in Select Regions (See Chart)

form

buffered aqueous solution

species reactivity

human

packaging

vial of 0.1 mL concentrate (161M-14), vial of 0.5 mL concentrate (161M-15), bottle of 1.0 mL predilute (161M-17), vial of 1.0 mL concentrate (161M-16), bottle of 7.0 mL predilute (161M-18)

manufacturer/tradename

Cell Marque®

technique(s)

immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:25-1:100

isotype

IgG1

control

bone marrow

shipped in

wet ice

storage temp.

2-8°C

visualization

cytoplasmic

Gene Information

human ... ITGB3(3690)

General description

CD61 also known as integrin beta chain beta 3 (ITGB3) is an integrin cell-surface protein associated with cellular adhesion and cell-surface mediated signaling. Immunohistochemical staining for CD61 can be useful in evaluating normal and abnormal megakaryocytes, which can aid in the identification of some hematopoietic malignancies. Anti-CD61 reactivity is also seen in platelets, osteoclasts, and macrophages.

Physical form

Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide

Preparation Note

Download the IFU specific to your product lot and formatNote: This requires a keycode which can be found on your packaging or product label.

Analysis Note


IVD

IVD

IVD

RUO

Other Notes

CD61 Positive Control Slides, Product No. 161S, are available for immunohistochemistry (formalin-fixed, paraffin-embedded sections).
For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com

Legal Information

Cell Marque is a registered trademark of Merck KGaA, Darmstadt, Germany


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存储类别

12 - Non Combustible Liquids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

法规信息

监管及禁止进口产品

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历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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J Thiele et al.
Analytical and quantitative cytology and histology, 12(4), 285-289 (1990-08-01)
On routinely processed trephine biopsies of the normal human bone marrow derived from 15 patients, immunostaining with a monoclonal antibody against platelet glycoprotein IIIa (Y2/51) and morphometric measurements were performed for the determination of megakaryocyte precursor cells. Based on cell
A Duperray et al.
Blood, 74(5), 1603-1611 (1989-10-01)
The platelet membrane glycoproteins GPIIb and GPIIIa form a calcium-dependent heterodimer that functions as a receptor for adhesive proteins on stimulated platelets. In this study, we have investigated the kinetics of the assembly reaction that result in GPIIb-IIIa dimerization. Pulse-chase
J Thiele et al.
Virchows Archiv. B, Cell pathology including molecular pathology, 58(4), 295-302 (1990-01-01)
To determine the number of megakaryocyte precursors (pro- and megakaryoblasts), an immunomorphometric study was performed on paraffin-embedded trephine biopsies of the bone marrow using a monoclonal antibody against platelet glycoprotein IIIa. Eighteen control specimens from patients with no evidence of



全球贸易项目编号

货号GTIN
161M-150841683125228
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161M-16-RUO04061836539771
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