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19899

CHAPS 100 mM 溶液

Name: CHAPS 100 mM 溶液
Brand: SIGMA

别名:

CHAPS 溶液

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关于此项目

经验公式（希尔记法）:

C₃₂H₅₈N₂O₇S

化学文摘社编号:

75621-03-3

分子量:

614.88

NACRES:

NA.25

PubChem Substance ID:

57647807

UNSPSC Code:

12161902

MDL number:

MFCD00012116

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属性

description

zwitterionic

Quality Level

100

form

liquid

mol wt

614.88 g/mol

concentration

100 mM in H₂O

technique(s)

protein quantification: suitable

CMC

8 mM

transition temp

cloud point >100 °C

density

1.01 g/mL at 20 °C

storage temp.

2-8°C

SMILES string

C[C@H](CCC(=O)NCCC[N+](C)(C)CCCS([O-])(=O)=O)[C@H]1CC[C@H]2[C@@H]3[C@H](O)CC4C[C@H](O)CC[C@]4(C)[C@H]3C[C@H](O)[C@]12C

InChI

1S/C32H58N2O7S/c1-21(8-11-29(38)33-14-6-15-34(4,5)16-7-17-42(39,40)41)24-9-10-25-30-26(20-28(37)32(24,25)3)31(2)13-12-23(35)18-22(31)19-27(30)36/h21-28,30,35-37H,6-20H2,1-5H3,(H-,33,38,39,40,41)/t21-,22?,23-,24-,25+,26+,27-,28+,30+,31+,32-/m1/s1

InChI key

UMCMPZBLKLEWAF-RFCNGIAKSA-N

说明

General description

3-[（3-胆固醇氨丙基）二甲基氨基]-1-丙磺酸（CHAPS）是一种生物相容性表面活性剂。它是胆酸的衍生物，包含疏水的胆固醇样骨架，具有三个羟基和一个两性离子脂肪族尾。

Application

CHAPS 100 mM 溶液可用作裂解缓冲液的成分，用于提取山羊子宫内膜上皮细胞（EEC）和肝组织的蛋白质。

Biochem/physiol Actions

3-[（3-胆固醇氨丙基）二甲基氨基]-1-丙磺酸（CHAPS）具有硫代甜菜碱型表面活性剂和胆汁盐的特性。它参与蛋白质组学分析用蛋白质的提取过程，并使膜蛋白重建进入脂质囊泡内部（蛋白脂质体）。CHAPS被广泛应用于生物化学领域膜蛋白和受体的分离和纯化。由于其生物相容性、无电荷特性、非变性和非聚集特性，它可用于药物和医学领域。

存储类别

12 - Non Combustible Liquids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves

历史批次信息供参考:

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全球贸易项目编号

货号	GTIN
19899-1ML-F	04061838762924