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Merck
CN

24368C

EX-CELL® Advanced CHO Feed 1 (without glucose)

别名:

EX-CELL® Advanced CHO Feed 1

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关于此项目

NACRES:
NA.71
UNSPSC Code:
12352200
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产品名称

EX-CELL® Advanced CHO Feed 1 (不含葡萄糖), CHO Feed 1 (without glucose). Use 34.10 g/L. See information sheet, 24368C @ www.sigmaaldrich.com for hydration instructions

Quality Level

product line

EX-CELL®

form

dry powder

technique(s)

cell culture | mammalian: suitable (suspension)

shipped in

ambient

storage temp.

2-8°C

General description

EX-CELL® Advanced CHO Feed 1 (不含葡萄糖)化学成分明确且不含有 动物来源成分。该补料用于分批补料平台 ,可与EX-CELL® Advanced CHO 分批补料培养基 (14366C或24366C)一起使用。 来自SAFC的最新平台经过特别开发设计, 用于维持分批补料培养物中各种中国仓鼠卵巢(CHO)细胞的生长和生产, 同时可灵活调节 蛋白质的质量属性。这种实时分批补料 平台采用多变量分析策略开发, 以确定配方成分影响关键过程和产品属性 (如滴度、 褶皱膨胀(fold expansion)、受体表达、 和T糖基化)的相关性。该平台不含次黄嘌呤和胸苷、 L-谷氨酰胺、酚红或2-巯基乙醇(2-ME)。

Preparation Note

按照每升培养基34.1克粉末配制。

Other Notes

提交EX-CELL Advanced CHO Fed-batch申请表以与SAFC代表取得联系。

Legal Information

EX-CELL is a registered trademark of Merck KGaA, Darmstadt, Germany


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Danger

Hazard Classifications

Eye Dam. 1 - Skin Irrit. 2 - Skin Sens. 1

存储类别

11 - Combustible Solids



历史批次信息供参考:

分析证书(COA)

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商品

In this study, nine commercially available, chemically defined media and feed combinations from different vendors were assessed for producing monoclonal antibody in Chinese hamster ovary (CHO) cells.

Discover how low-impurity iron sources improve reliability and performance in recombinant protein production with EX-CELL® Advanced medium.

Optimizing feed for upstream cell culture improves monoclonal antibody production, but requires balancing outcomes for both viable cell density and productivity.

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Pao-Chun Lin et al.
mAbs, 11(5), 965-976 (2019-05-03)
Chinese hamster ovary (CHO) cells are the biopharmaceutical industry's primary means of manufacturing therapeutic proteins, including monoclonal antibodies. The major challenge in cell line development for the production of recombinant biopharmaceuticals lies in generating and isolating rare high-producing stable clones



全球贸易项目编号

货号GTIN
24368C-25K04061834411567
24368C-50L04061838821829
24368C-10L04061838822031
24368C-1L04061838822048
24368C-50K04061834411574