27029
胆酸钠 水合物
≥97.0% (dried material, NT)
别名:
3α,7α,12α-三羟基-5β-胆甾烷-24-羧酸 钠盐, 胆酸 钠盐
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关于此项目
经验公式（希尔记法）:
C24H39NaO5 · xH2O
化学文摘社编号:
分子量:
430.55 (anhydrous basis)
UNSPSC Code:
12161900
NACRES:
NA.25
PubChem Substance ID:
EC Number:
206-643-5
Beilstein/REAXYS Number:
3582354
MDL number:
description
anionic
Quality Level
assay
≥97.0% (dried material, NT)
form
powder
optical activity
[α]/D 26.0 to 34.0°°, c = 2% (solution in purified water, CALCULATED FOR DRIED SUBSTANCE)
mol wt
micellar avg mol wt 900-1300
aggregation number
2-3
loss
≤5% loss on drying
CMC
9-15 mM (20-25°C)
solubility
H2O: 0.1 M, H2O: 100 mg/mL
HLB
18
SMILES string
O.[Na+].C[C@H](CCC([O-])=O)C1CCC2C3[C@H](O)CC4C[C@H](O)CC[C@]4(C)C3C[C@H](O)[C@]12C
InChI
1S/C24H40O5.Na.H2O/c1-13(4-7-21(28)29)16-5-6-17-22-18(12-20(27)24(16,17)3)23(2)9-8-15(25)10-14(23)11-19(22)26;;/h13-20,22,25-27H,4-12H2,1-3H3,(H,28,29);;1H2/q;+1;/p-1/t13-,14+,15-,16-,17+,18+,19-,20+,22+,23+,24-;;/m1../s1
InChI key
MUVVIYFKOVLQHL-RCVKHMDESA-M
General description
水合胆酸钠是一种生物表面活性剂，可作为水溶液中的还原剂。
水合胆酸钠是一种非变性阴离子洗涤剂。
Application
- 经皮给药的优化：应用于超弹性纳米囊泡配方中的水合胆酸钠可提高地夫可特（deflazacort）的生物利用度和抗炎功效，展现了其在经皮给药系统中的潜力，可用于诊断目的（Ali et al., 2021）。
- 用于IVD的纳米载体配方：该研究利用水合胆酸钠对胆汁体（bilosome）进行表面改性，其可作为杂化化合物的功能性和生物相容性纳米载体，该方法适用于创新IVD试剂的设计（Waglewska et al., 2020）。
- 用于皮肤给药的体外诊断试剂配方：水合胆酸钠在用于递送抗氧化剂的纳米传递体开发中发挥了重要作用，研究显示了其在创造具有抗氧化和抗衰老作用的皮肤应用诊断试剂中的作用（Avadhani et al., 2017）。
- 纳米技术中的分级和分离技术：水合胆酸钠显示了亲和力介导的分级顺序逆转（sorting order reversal）特性，它在密度梯度超速离心技术中至关重要，研究突显了其在诊断分析材料的精确分级和制备中的用途（Jang et al., 2016）
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hcodes
pcodes
Hazard Classifications
Aquatic Chronic 3
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
Ewelina Waglewska et al.
Nanomaterials (Basel, Switzerland), 10(12) (2020-12-17)
In the present contribution, we demonstrate a new approach for functionalization of colloidal nanomaterial consisting of phosphatidylcholine/cholesterol-based vesicular systems modified by FDA-approved biocompatible components, i.e., sodium cholate hydrate acting as a biosurfactant and Pluronic P123-a symmetric triblock copolymer comprising poly(ethylene
Sonia Biccai et al.
ACS nano, 13(6), 6845-6855 (2019-06-15)
Nanocomposite strain sensors, particularly those consisting of polymer-graphene composites, are increasingly common and are of great interest in the area of wearable sensors. In such sensors, application of strain yields an increase in resistance due to the effect of deformation
Jilite Wang et al.
Bioscience, biotechnology, and biochemistry, 79(3), 456-461 (2014-11-07)
Dietary plant protein is well known to reduce serum cholesterol levels. Rice bran is a by-product of rice milling and is a good source of protein. The present study examined whether feeding rats a high-cholesterol diet containing 10% rice bran
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| 27029-100G-F | 04061826141878 |
| 27029-500G-F | 04061833440261 |