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Merck
CN

30165

替罗非班

≥98.5% (HPLC)

别名:

N-(丁基磺酰基)-O-[4-(4-哌啶基)丁基]-L-酪氨酸, (2S)-2-(丁基磺酰基氨基)-3-{4-[4-(4-哌啶基)丁氧基}苯基丙酸

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关于此项目

经验公式(希尔记法):
C22H36N2O5S
化学文摘社编号:
分子量:
440.60
UNSPSC Code:
12352106
NACRES:
NA.25
PubChem Substance ID:
MDL number:
Beilstein/REAXYS Number:
6182267
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Quality Level

assay

≥98.5% (HPLC)

form

powder

SMILES string

CCCCS(=O)(=O)N[C@@H](Cc1ccc(OCCCCC2CCNCC2)cc1)C(O)=O

InChI

1S/C22H36N2O5S/c1-2-3-16-30(27,28)24-21(22(25)26)17-19-7-9-20(10-8-19)29-15-5-4-6-18-11-13-23-14-12-18/h7-10,18,21,23-24H,2-6,11-17H2,1H3,(H,25,26)/t21-/m0/s1

InChI key

COKMIXFXJJXBQG-NRFANRHFSA-N

Gene Information

Application


  • The efficacy and safety of continuous intravenous tirofiban for acute ischemic stroke patients treated by endovascular therapy: a meta-analysis.:通过meta分析评估急性缺血性卒中患者血管内治疗中连续静脉给药替罗非班的疗效和安全性,具有改善疗效的满意结果(Wang et al., 2024)。

  • Initial Experience with a New Self-Expanding Open-Cell Stent System with Antithrombotic Hydrophilic Polymer Coating (pEGASUS Stent) in the Treatment of Wide-Necked Intracranial Aneurysms.:研究报道首次用新的涂层支架系统治疗颅内动脉瘤(有用到替罗非班),结果疗效和安全性增强(Boxberg et al., 2024)。

Packaging

无底玻璃瓶。内含物装在插入的融合锥内。


pictograms

Exclamation mark

signalword

Warning

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves



历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Christoph Kabbasch et al.
Journal of neurointerventional surgery, 11(8), 812-816 (2019-01-25)
Intrasaccular flow disruption represents a new paradigm in endovascular treatment of wide-necked bifurcation aneurysms. To perform a matched case-control study comparing complications and angiographic outcome using the Woven Endobridge (WEB) device and stent-assisted coiling (SAC). Sixty-six patients treated with the
Lukas Goertz et al.
World neurosurgery, 126, e965-e974 (2019-03-17)
Woven Endobridge (WEB) embolization is an approved technique for endovascular treatment of wide-necked and bifurcation aneurysms. However, the WEB has not yet been routinely used for internal carotid artery (ICA) sidewall aneurysms. In this multicenter study, we evaluate the safety
Nohra Chalouhi et al.
Neurosurgery, 71(3), 710-714 (2012-06-07)
Thromboembolic complications are a major concern in stent-assisted coiling of intracranial aneurysms that may be prevented with adequate antiplatelet therapy. To assess the safety and efficacy of tirofiban in stent-assisted coiling. Two protocols were used. In the initial protocol, tirofiban



全球贸易项目编号

货号GTIN
30165-5MG04061832860169