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Merck
CN

30170

L-磺基丙氨酸 一水合物

≥99.0% (T), suitable for LC/MS

别名:

L-氧化半胱氨酸

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关于此项目

线性分子式:
HO3SCH2CH(NH2)CO2H·H2O
化学文摘社编号:
分子量:
187.17
NACRES:
NA.26
PubChem Substance ID:
UNSPSC Code:
12352209
MDL number:
Beilstein/REAXYS Number:
3714036
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产品名称

L-磺基丙氨酸 一水合物, ≥99.0% (T)

Quality Level

assay

≥99.0% (T)

form

powder or crystals

optical activity

[α]20/D +7.5±0.5°, c = 5% in H2O

technique(s)

LC/MS: suitable

color

white to faint yellow

mp

267 °C (dec.) (lit.)

solubility

H2O: soluble

application(s)

peptide synthesis

SMILES string

[H]O[H].N[C@@H](CS(O)(=O)=O)C(O)=O

InChI

1S/C3H7NO5S.H2O/c4-2(3(5)6)1-10(7,8)9;/h2H,1,4H2,(H,5,6)(H,7,8,9);1H2/t2-;/m0./s1

InChI key

PCPIXZZGBZWHJO-DKWTVANSSA-N

Application

氨基酸分析的内标。

Biochem/physiol Actions

L-半胱磺酸是一种 L-半胱氨酸的氧化产物。L-半胱磺酸是半胱氨酸亚磺酸的类似物,可用于研究脑中的兴奋性氨基酸,例如与半胱氨酸亚磺酸受体结合的氨基酸。L-半胱磺酸是几种大鼠代谢型谷氨酸受体(mGluRs)的有用的激动剂。
L-半胱磺酸是含硫的天冬氨酸类似物,其可以用作细菌天冬氨酸:丙氨酸反向转运体(AspT)交换天冬氨酸和其他天冬氨酸生物系统的竞争性抑制剂。L-半胱磺酸用于单体表面活性剂的开发。


存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)



历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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B Meldrum
Epilepsia, 25 Suppl 2, S140-S149 (1984-01-01)
Amino acids provide the most universal and important inhibitory (gamma-aminobutyric acid (GABA), glycine) and excitatory (glutamate, aspartate, cysteic acid, cysteine sulphinic acid) neurotransmitters in the brain. An anticonvulsant action may be produced (1) by enhancing inhibitory (GABAergic) processes, and (2)
Internal standards for amino acid analysis.
J F Riordan et al.
Methods in enzymology, 47, 31-40 (1977-01-01)
Qi Shi et al.
The Journal of pharmacology and experimental therapeutics, 305(1), 131-142 (2003-03-22)
Moderate hyperhomocysteinemia is associated with several diseases, including coronary artery disease, stroke, Alzheimer's disease, schizophrenia, and spina bifida. However, the mechanisms for their pathogenesis are unknown but could involve the interaction of homocysteine or its metabolites with molecular targets such



全球贸易项目编号

货号GTIN
30170-10G04061826665510
30170-50G04061832719054