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319M-1

Cytokeratin 19 (A53-B/A2.26) Mouse Monoclonal Antibody

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关于此项目

NACRES:
NA.41
UNSPSC Code:
12352203
Conjugate:
unconjugated
Clone:
A53-B/A2.26, monoclonal
Application:
IHC (p)
Citations:
9
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biological source

mouse

Quality Level

100, 500

conjugate

unconjugated

antibody form

diluted ascites fluid

antibody product type

primary antibodies

clone

A53-B/A2.26, monoclonal

description

For In Vitro Diagnostic Use in Select Regions (See Chart)

form

buffered aqueous solution

species reactivity

human

packaging

vial of 0.1 mL concentrate (319M-14), vial of 0.5 mL concentrate (319M-15), bottle of 1.0 mL predilute (319M-17), vial of 1.0 mL concentrate (319M-16), bottle of 7.0 mL predilute (319M-18)

manufacturer/tradename

Cell Marque®

technique(s)

immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:100-1:500

isotype

IgG2aλ

control

colon

shipped in

wet ice

storage temp.

2-8°C

visualization

cytoplasmic

Gene Information

human ... KRT19(3880)

General description

Anti-cytokeratin 19 reacts with simple and complex epithelia, including the glandular andductal epithelium of organs such as the gastrointestinal tract and breast and squamousepithelium. CK19 expression is seen in many carcinomas, including carcinomas of the colon,stomach, pancreas, biliary tract, liver, and breast. Anti-cytokeratin 19 has been used tohelp identify neoplasms in the liver and as an aid in the identification of thyroid papillarycarcinoma.

Physical form

Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide

Preparation Note

Download the IFU specific to your product lot and formatNote: This requires a keycode which can be found on your packaging or product label.

Analysis Note


IVD
IVD
IVD
RUO

Other Notes

Cytokeratin 19 Positive Control Slides , Product No. 319S, are available for immunohistochemistry (formalin-fixed, paraffin-embedded sections).
For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com

Legal Information

Cell Marque is a registered trademark of Merck KGaA, Darmstadt, Germany

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存储类别

12 - Non Combustible Liquids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

法规信息

监管及禁止进口产品

此项目有

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number
0000288551
0000288551
1505616A-Z
1412506A-Z

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胃肠道癌症中的免疫组织化学应用

结直肠癌是男性和女性中第三大常见癌症。预计2016年将发生136,000例结直肠癌。

Immunohistochemistry Applications in Gastrointestinal Cancer

Colorectal cancer is the third most common cancer in both men and women. An estimated 136,000 cases of colorectal cancer are expected to occur in 2016.

Lisa A Cerilli et al.
American journal of clinical pathology, 118(2), 186-193 (2002-08-07)
We applied monoclonal antibodies against RET and cytokeratin 19 (CK19) to the following tumor sections: classic papillary carcinoma (PC), 16; Hürthle-type PC (HPC), 1; sclerosing PC with nodular fasciitis-like stroma (SPC), 1; PC, follicular variant (FVPC), 12; follicular adenoma (FA)
S M Nasser et al.
Cancer, 90(5), 307-311 (2000-10-20)
Papillary thyroid carcinoma is the most common malignant neoplasm of the thyroid gland, and fine-needle aspiration biopsy (FNAB) often is the initial diagnostic method used in its detection. Prior studies have shown that immunohistochemical staining for various cytokeratins in general
M F Beesley et al.
Histopathology, 41(3), 236-243 (2002-09-05)
The immunohistochemical expression of cytokeratin 19 (CK 19) and galectin-3 was evaluated in 69 thyroid lesions to assess their potential as markers in the diagnosis and classification of thyroid malignancy. The following were studied: 26 cases of papillary carcinoma, 12
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