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466R-1

SDHB (EP288) Rabbit Monoclonal Primary Antibody

Name: SDHB (EP288) Rabbit Monoclonal Primary Antibody
Brand: SIGMA

别名:

Succinate dehydrogenase B

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关于此项目

UNSPSC Code:

12352203

Conjugate:

unconjugated

Clone:

EP288, monoclonal

Application:

IHC (p)

Citations:

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属性

biological source

rabbit

Quality Level

100, 500

conjugate

unconjugated

antibody form

culture supernatant

antibody product type

primary antibodies

clone

EP288, monoclonal

description

For In Vitro Diagnostic Use in Select Regions

form

buffered aqueous solution

species reactivity

human

packaging

vial of 0.1 mL concentrate (466R-14), vial of 0.1 mL concentrate Research Use Only (466R-14-RUO), vial of 0.5 mL concentrate (466R-15), vial of 1.0 mL concentrate (466R-16), vial of 1.0 mL concentrate Research Use Only (466R-16-RUO), vial of 1.0 mL pre-dilute Research Use Only (466R-17-RUO), vial of 1.0 mL pre-dilute ready-to-use (466R-17), vial of 7.0 mL pre-dilute ready-to-use (466R-18), vial of 7.0 mL pre-dilute ready-to-use Research Use Only (466R-18-RUO)

manufacturer/tradename

Cell Marque^®

technique(s)

immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:25-1:100 (concentrated)

isotype

IgG

control

GIST

shipped in

wet ice

storage temp.

2-8°C

visualization

cytoplasmic

Gene Information

human ... SDHB(6390)

说明

General description

Succinate dehydrogenase B (SDHB) is an iron-sulfur subunit of mitochondrial complex II, a respiratory complex that catalyzes the oxidation of succinate in the mitochondrial membrane. Many cancers are generally positive for SDHB, including renal cell carcinomas (RCC) and gastrointestinal stromal tumors (GIST). However, a subset of RCC and GIST tumors that are associated with SDH mutations, Carney-Stratakis Syndrome or Carney Triad exhibit a loss of SDHB expression.

Physical form

Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide.

Preparation Note

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Analysis Note

IVD

RUO

Other Notes

For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com

Legal Information

Cell Marque is a registered trademark of Merck KGaA, Darmstadt, Germany

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存储类别

12 - Non Combustible Liquids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c