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关于此项目
经验公式（希尔记法）:
C21H11NO5S
化学文摘社编号:
分子量:
389.38
UNSPSC Code:
12171500
NACRES:
NA.32
PubChem Substance ID:
EC Number:
248-207-7
Beilstein/REAXYS Number:
1407295
MDL number:
product line
BioReagent
assay
≥90% (HPLC)
form
powder
mol wt
389.38 g/mol
color
orange to dark orange, yellow to dark yellow
solubility
acetone: 0.1 g/10 mL, clear to very slightly hazy
fluorescence
λex 492 nm; λem 518 nm in 0.1 M phosphate pH 8.0
suitability
suitable for fluorescence
storage temp.
−20°C
SMILES string
Oc1ccc2c(Oc3cc(O)ccc3C24OC(=O)c5cc(ccc45)N=C=S)c1
InChI
1S/C21H11NO5S/c23-12-2-5-16-18(8-12)26-19-9-13(24)3-6-17(19)21(16)15-4-1-11(22-10-28)7-14(15)20(25)27-21/h1-9,23-24H
InChI key
MHMNJMPURVTYEJ-UHFFFAOYSA-N
General description
荧光素5（6）-异硫氰酸酯，也称为FITC，是一种弱酸性的羟基黄酮类化合物，其整体尺寸较小，在苯环上具有羧酸和异硫氰酸酯基团。这种染料具有中等大小、非平面的芳香环系。 异硫氰酸酯基团与生物分子的亲核官能团（如氨基，羟基，巯基）反应，作为荧光标记物附加在生物分子上。 该染料在相同溶剂中的最大发射波长为519纳米。
Application
用于蛋白质的荧光标记（例如免疫荧光）;凝胶色谱中的 H 蛋白质标记
荧光素5(6)-异硫氰酸(FITC)标记的分子用于非显微免疫测定和生理示踪实验。FITC在流式细胞术实验中广泛用于蛋白质、细胞核和亚核颗粒的染色。 使用FITC标记的白细胞（WBC）可用于研究其对趋化因子的反应性并进行最终测定。
Packaging
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存储类别
11 - Combustible Solids
ppe
dust mask type N95 (US), Eyeshields, Faceshields, Gloves
signalword
Warning
hcodes
Hazard Classifications
Acute Tox. 4 Oral - Skin Irrit. 2 - Skin Sens. 1B
Wenhuo Hu et al.
Blood, 125(14), 2206-2216 (2015-01-31)
Hematopoietic stem cells (HSCs) possess the ability to generate all hematopoietic cell types and to self-renew over long periods, but the mechanisms that regulate their unique properties are incompletely understood. Herein, we show that homozygous deletion of the miR-29a/b-1 bicistron
Marina Vivarelli et al.
Kidney international, 87(3), 602-609 (2015-01-08)
Alloimmune antenatal membranous nephropathy (MN) during pregnancy results from antibodies produced by a neutral endopeptidase (NEP)-deficient mother. Here we report two recent cases that provide clues to the severity of renal disease. Mothers of the two children had circulating antibodies
Benoit Malleret et al.
Blood, 125(8), 1314-1324 (2014-11-22)
Plasmodium vivax merozoites only invade reticulocytes, a minor though heterogeneous population of red blood cell precursors that can be graded by levels of transferrin receptor (CD71) expression. The development of a protocol that allows sorting reticulocytes into defined developmental stages
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| 46950-50MG-F | 04061832358949 |
| 46950-1G-F | 04061832358925 |
| 46950-250MG-F | 04061832358932 |