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Merck
CN

50937

胍 盐酸盐 溶液

BioUltra, ~8 M in H2O

别名:

亚氨基脲 盐酸盐, 盐酸胍, 胍盐酸盐

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关于此项目

经验公式(希尔记法):
CH5N3 · HCl
化学文摘社编号:
分子量:
95.53
UNSPSC Code:
12352107
NACRES:
NA.25
PubChem Substance ID:
MDL number:
Beilstein/REAXYS Number:
3591990
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product line

BioUltra

Quality Level

form

liquid

concentration

~8 M in H2O

impurities

insoluble matter, passes filter test

refractive index

n20/D 1.465

pH

4.5-7.5 (25 °C)

anion traces

sulfate (SO42-): ≤50 mg/kg

cation traces

Al: ≤1 mg/kg, As: ≤0.1 mg/kg, Ba: ≤1 mg/kg, Bi: ≤1 mg/kg, Ca: ≤10 mg/kg, Cd: ≤1 mg/kg, Co: ≤1 mg/kg, Cr: ≤1 mg/kg, Cu: ≤1 mg/kg, Fe: ≤1 mg/kg, K: ≤20 mg/kg, Li: ≤1 mg/kg, Mg: ≤5 mg/kg, Mn: ≤1 mg/kg, Mo: ≤1 mg/kg, Na: ≤150 mg/kg, Ni: ≤1 mg/kg, Pb: ≤1 mg/kg, Sr: ≤1 mg/kg, Zn: ≤1 mg/kg

λ

neat

UV absorption

λ: 260 nm Amax: 0.040, λ: 280 nm Amax: 0.025

SMILES string

Cl.NC(N)=N

InChI

1S/CH5N3.ClH/c2-1(3)4;/h(H5,2,3,4);1H

InChI key

PJJJBBJSCAKJQF-UHFFFAOYSA-N

Application

盐酸胍溶液已被用作固定缓冲液,用于基因组分析中基因组DNA的提取。

Biochem/physiol Actions

盐酸胍(Gnd-HCl)是一种高效的离液剂(chaotropic agent),作为变性剂被广泛用于RNA分离、球蛋白变性和蛋白质复性研究。它是一种合适的样品缓冲剂,可用于亲和纯化的蛋白质复合物的快速有效的洗脱,以及之后的蛋白质消化步骤。由于其在低摩尔浓度下抑制胰蛋白酶活性,并且在与十二烷基硫酸钠(SDS)结合时有形成沉淀的倾向,盐酸胍不适用于蛋白质组学实验。盐酸胍常用于从富含细胞外基质(ECM)‐的组织(包括骨骼、软骨、韧带和肌腱)中提取蛋白质。


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pictograms

Exclamation mark

signalword

Warning

Hazard Classifications

Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2

存储类别

10 - Combustible liquids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter



历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Fackson Mwale et al.
Tissue engineering. Part A, 20(21-22), 2942-2949 (2014-05-03)
Link N is a naturally occurring peptide that can stimulate proteoglycan synthesis in intervertebral disc (IVD) cells. IVD repair can also potentially be enhanced by mesenchymal stem cell (MSC) supplementation to maximize extracellular matrix (ECM) production. In a previous study
Lizhen Qiao et al.
Journal of chromatography. A, 1276, 112-119 (2013-01-15)
Room temperature ionic liquids (RTILs) as stationary phases for gas chromatography (GC) have made great achievements in both research and applications over the last decades. Until now, all of the RTIL stationary phases reported have involved imidazolium, ammonium, pyrrolidinium, and
Caitriona McKeever et al.
Journal of medicinal chemistry, 56(3), 700-711 (2013-01-11)
Considering the strong DNA minor groove binding observed for our previous series of diaromatic symmetric and asymmetric guanidinium and 2-aminoimidazolinium derivatives, we report now the synthesis of new aminoalkyl derivatives of diaromatic guanidines with potential as DNA minor groove binders



全球贸易项目编号

货号GTIN
50937-100ML04061832489711