54880
3-羟基苄肼 二盐酸盐
≥98.0% (HPLC)
别名:
α-肼基-间-甲酚 二盐酸盐, 3-(肼基甲基)苯酚 二盐酸盐, NSD-1015
登录 查看组织和合同定价。
选择尺寸
变更视图
关于此项目
线性分子式:
HOC6H4CH2NHNH2 · 2HCl
化学文摘社编号:
分子量:
211.09
UNSPSC Code:
12352202
NACRES:
NA.77
PubChem Substance ID:
EC Number:
279-659-3
Beilstein/REAXYS Number:
9282965
MDL number:
Quality Level
assay
≥98.0% (HPLC)
form
solid
mp
137-140 °C, 138-140 °C (lit.)
solubility
H2O: 50 mg/mL, slightly hazy, faintly yellow
SMILES string
Cl[H].Cl[H].NNCc1cccc(O)c1
InChI
1S/C7H10N2O.2ClH/c8-9-5-6-2-1-3-7(10)4-6;;/h1-4,9-10H,5,8H2;2*1H
InChI key
ONOJPUDFIOEGCX-UHFFFAOYSA-N
Biochem/physiol Actions
L-芳香族氨基酸脱羧酶抑制剂；穿过血脑屏障。还可通过形成该辅因子的3-羟基苄基腙，还抑制GABA转氨酶以及其他需要磷酸吡哆醛的酶。
L-芳香族氨基酸脱羧酶抑制剂；穿过血脑屏障。
signalword
Danger
hcodes
Hazard Classifications
Acute Tox. 4 Oral - Eye Dam. 1 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Faceshields, Gloves
商品
血清素（5-羟色胺）主要存在于三种主要细胞类型中：i）中杻神经系统（CNS）和肠肌间神经丛中的血清素能神经元，ii）胃肠道粘膜中的肠嗜铬细胞，和iii）血小板。血清素的代谢主要通过外部线粒体膜酶单胺氧化酶（MAO）进行，它以两种分子亚型存在，分别称为MAO-A和MAO-B。
Serotonin is stored in cells and metabolized by MAO, influencing CNS, GI, and platelet functions.
Gerard Honig et al.
PloS one, 4(8), e6797-e6797 (2009-08-28)
Serotonin (5-HT) is a neurotransmitter with important roles in the regulation of neurobehavioral processes, particularly those regulating affect in humans. Drugs that potentiate serotonergic neurotransmission by selectively inhibiting the reuptake of serotonin (SSRIs) are widely used for the treatment of
V Mosienko et al.
Translational psychiatry, 2, e122-e122 (2012-07-27)
Serotonin is a major neurotransmitter in the central nervous system (CNS). Dysregulation of serotonin transmission in the CNS is reported to be related to different psychiatric disorders in humans including depression, impulsive aggression and anxiety disorders. The most frequently prescribed
Noriko Wakabayashi-Ito et al.
PloS one, 6(10), e26183-e26183 (2011-10-25)
Dystonia represents the third most common movement disorder in humans. At least 15 genetic loci (DYT1-15) have been identified and some of these genes have been cloned. TOR1A (formally DYT1), the gene responsible for the most common primary hereditary dystonia
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| 54880-1G-F | 04061832574912 |
| 54880-5G-F | 04061833021781 |