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Merck
CN

69554

肽聚糖 来源于枯草芽孢杆菌

别名:

PGN

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关于此项目

UNSPSC Code:
41116134
NACRES:
NA.21
MDL number:
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form

solid

Quality Level

storage temp.

−20°C

General description

肽聚糖。是一种生物聚合物,是革兰氏阳性菌细胞壁的主要成分。肽聚糖由 N -乙酰基葡糖胺和 N -乙酰基胞壁酸交替单位的碳水化合物骨架组成,并被 D -和 L -氨基酸修饰。 N -乙酰胞壁酸残基与寡肽交联。末端肽为 D -丙氨酸,但其他氨基酸以 D -异构体存在。

Application

肽聚糖可用于裂解酶(如裂解酶)的活性评估。建议使用浓度为 0.15-3μ 的肽聚糖g/ml,溶于水或缓冲液,在 450 nm 处测定。肽聚糖不溶解,但在水中产生混悬液。
肽聚糖可激活 Toll 样受体 2 (TLR2),TLR2 存在于哺乳动物细胞中以刺激淋巴细胞。也可作为 Poly (I:C) 的拮抗剂发挥作用。

Packaging

无底玻璃瓶。内含物在插入的融合锥体内。


存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)



历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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商品

肽聚糖(PGN)的基本结构含有N-乙酰葡糖胺(GlcNAc)与N-乙酰胞壁酸交替单元的碳水化合物主链,其中N-乙酰胞壁酸残基与肽交联。

Peptidoglycan structure: alternating GlcNAc and N-acetylmuramic acid cross-linked to peptides form the basic backbone.


Angela Cuttitta et al.
Fish & shellfish immunology, 67, 86-94 (2017-06-06)
Gene family encoding allograft inflammatory factor-1 (AIF-1) is well conserved among organisms; however, there is limited knowledge in lower organisms. In this study, the first AIF-1 homologue from cnidarians was identified and characterised in the sea anemone Anemonia viridis. The
Yichao Xie et al.
Fish & shellfish immunology, 106, 384-392 (2020-08-11)
Antimicrobial peptide (AMP) is a crucial component of the innate immune system in crustaceans. In mud crab, Scylla paramamosain, a commercially important species, a glycine-rich antimicrobial peptide (Spgly-AMP) gene was newly identified and putatively encoded a 26aa signal peptide and
Christian Stelter et al.
PloS one, 6(6), e20749-e20749 (2011-06-23)
Intestinal inflammation induces alterations of the gut microbiota and promotes overgrowth of the enteric pathogen Salmonella enterica by largely unknown mechanisms. Here, we identified a host factor involved in this process. Specifically, the C-type lectin RegIIIβ is strongly upregulated during



全球贸易项目编号

货号GTIN
69554-10MG-F04061833278079