72309
烟酸
≥99.5% (HPLC)
别名:
3-吡啶甲酸, 吡啶-3-羧酸, 尼亚生, 抗糙皮病因子, 维生素 B3
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关于此项目
经验公式（希尔记法）:
C6H5NO2
化学文摘社编号:
分子量:
123.11
UNSPSC Code:
12352209
NACRES:
NA.26
PubChem Substance ID:
EC Number:
200-441-0
Beilstein/REAXYS Number:
109591
MDL number:
biological source
synthetic
Quality Level
assay
≥99.5% (HPLC)
form
powder
technique(s)
cell culture | mammalian: suitable
impurities
≤0.2% water
ign. residue
≤0.05%
color
colorless to white
mp
234-238 °C, 236-239 °C (lit.)
solubility
water: 0.1 g/10 mL, clear, colorless
density
1.473 g/cm3 at 25 °C
SMILES string
OC(=O)c1cccnc1
InChI
1S/C6H5NO2/c8-6(9)5-2-1-3-7-4-5/h1-4H,(H,8,9)
InChI key
PVNIIMVLHYAWGP-UHFFFAOYSA-N
Gene Information
human ... CYP1A2(1544)
rat ... Chrnb2(54239)
General description
烟酸，也被称为维生素B3，是一种水溶性维生素。它存在于富含维生素的面包、肝脏、肉、鱼、家禽、土豆、绿色蔬菜、花生和谷物中。
Application
烟酸已在NAD+ 前体救援实验中被用作标准品。它也已被用作多种培养基（例如完全培养基（CM））和合成培养基中的维生素补充剂。
Biochem/physiol Actions
烟酸可通过减少低密度脂蛋白（LDL），增加高密度脂蛋白（HDL）并抑制动脉粥样硬化和冠状动脉病变的发展来调节脂质代谢。烟酸缺乏会导致糙皮病。除作为维生素补充剂外，烟酸还可用作广谱脂质药物。
Other Notes
Coenzyme and Cofactors, vol 2: Pyridine Nucleotide Coenzymes
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signalword
Warning
hcodes
Hazard Classifications
Eye Irrit. 2
存储类别
11 - Combustible Solids
wgk
WGK 1
flash_point_f
379.4 °F - closed cup
flash_point_c
193 °C - closed cup
ppe
dust mask type N95 (US), Eyeshields, Gloves
Chemical, Biochemical and Medical Aspects, 776-776 null
NAMPT-mediated NAD+ biosynthesis in adipocytes regulates adipose tissue function and multi-organ insulin sensitivity in mice
Stromsdorfer KL, et al.
Testing, 16(7), 1851-1860 (2016)
Nutrition and Food Safety
The New Public Health (2015)
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| 72309-100G | 04061832861029 |
| 72309-500G | 04061832861036 |