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Merck
CN

72559

次氮基三乙酸

BioUltra, ≥99.0% (T)

别名:

N,N-二(羧甲基)甘氨酸, NTA, 三(羧甲基)胺

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关于此项目

线性分子式:
N(CH2COOH)3
化学文摘社编号:
分子量:
191.14
UNSPSC Code:
12352102
NACRES:
NA.25
PubChem Substance ID:
EC Number:
205-355-7
Beilstein/REAXYS Number:
1710776
MDL number:
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product line

BioUltra

Quality Level

assay

≥99.0% (T)

form

powder

reaction suitability

reagent type: reductant

impurities

insoluble matter, passes filter test

ign. residue

≤0.05%

loss

≤0.1% loss on drying, 110 °C

pH

1.7-2.7 (23 °C, 10 g/L)

mp

245 °C (dec.) (lit.)

solubility

0.1 M NaOH: 0.1 M at 20 °C, clear, colorless

anion traces

chloride (Cl-): ≤100 mg/kg

cation traces

Al: ≤20 mg/kg, As: ≤0.1 mg/kg, Ba: ≤5 mg/kg, Bi: ≤5 mg/kg, Ca: ≤10 mg/kg, Cd: ≤5 mg/kg, Co: ≤5 mg/kg, Cr: ≤5 mg/kg, Cu: ≤5 mg/kg, Fe: ≤20 mg/kg, K: ≤50 mg/kg, Li: ≤5 mg/kg, Mg: ≤5 mg/kg, Mn: ≤5 mg/kg, Mo: ≤5 mg/kg, Na: ≤500 mg/kg, Ni: ≤5 mg/kg, Pb: ≤5 mg/kg, Sr: ≤5 mg/kg, Zn: ≤5 mg/kg

λ

0.1 M in 1 M NaOH

UV absorption

λ: 260 nm Amax: 1.5, λ: 280 nm Amax: 0.05

SMILES string

OC(=O)CN(CC(O)=O)CC(O)=O

InChI

1S/C6H9NO6/c8-4(9)1-7(2-5(10)11)3-6(12)13/h1-3H2,(H,8,9)(H,10,11)(H,12,13)

InChI key

MGFYIUFZLHCRTH-UHFFFAOYSA-N

Application

Nitrilotriacetic has been used in the preparation of nitrilotriacetic (NTA) solution for Ni-NTA slide generation.
一种优质的螯合剂。

Biochem/physiol Actions

Nitrilotriacetic (NTA) has the ability to link with histidine side chain of proteins. It can be used in fluorescent labelling, hexahistidine (His6)-tagged proteins for purification and surface immobilization.

Other Notes

Chelating agent; As Pb2+ buffer, preparation and properties; In a mixture of Ca2+-buffering ligands; Encapsulation of radioactive metal ions in liposomes; Compilation and critical evaluation by IUPAC of published data on stability constants of NTA complexes in solution.


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Health hazardExclamation mark

signalword

Warning

Hazard Classifications

Acute Tox. 4 Oral - Carc. 2 - Eye Irrit. 2

存储类别

11 - Combustible Solids

wgk

WGK 2

flash_point_f

212.0 °F - closed cup

flash_point_c

100 °C - closed cup

ppe

Eyeshields, Gloves, type P3 (EN 143) respirator cartridges



历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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K J Hwang et al.
Biochimica et biophysica acta, 716(1), 101-109 (1982-05-05)
The encapsulation of radioactive metalic cations, such as 111In3+ or 67Ga3+, in the internal aqueous compartment of liposomes can be achieved with an efficiency of about 90%. The efficient loading of a high specific activity of cations into liposomes involves
G. Anderegg
Pure and Applied Chemistry. Chimie Pure Et Appliquee, 54, 2693-2693 (1982)
In situ, Cell-free Protein Expression on Microarrays and Their Use for the Detection of Immune Responses
Hufnagel K, et al.
Scientific Reports, 28(10), 2412-2412 (2017)



全球贸易项目编号

货号GTIN
123897-1G04061838722621
35487-100MG04061831812077
43537-50MG04061833950159
72559-100G04061832861838
72559-500G04061833441008