86339
牛胆酸钠 水合物
≥97.0% (TLC)
别名:
牛磺胆酸 钠盐
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关于此项目
经验公式（希尔记法）:
C26H44NNaO7S · xH2O
化学文摘社编号:
分子量:
537.68 (anhydrous basis)
UNSPSC Code:
12161902
NACRES:
NA.77
PubChem Substance ID:
EC Number:
205-653-7
Beilstein/REAXYS Number:
3901620
MDL number:
Quality Level
biological source
ox bile, synthetic
description
anionic
assay
≥97.0% (TLC)
form
powder
optical activity
[α]20/D +23±1°, c = 3% in H2O (dry matter)
mol wt
537.68 g/mol (anhydrous basis)
impurities
≤1% taurine, ≤2% cholic acid
solubility
H2O: 50 mg/mL, clear
functional group
sulfonic acid
SMILES string
O.[Na+].C[C@H](CCC(=O)NCCS([O-])(=O)=O)[C@H]1CC[C@H]2[C@@H]3[C@H](O)C[C@@H]4C[C@H](O)CC[C@]4(C)[C@H]3C[C@H](O)[C@]12C
InChI
1S/C26H45NO7S.Na.H2O/c1-15(4-7-23(31)27-10-11-35(32,33)34)18-5-6-19-24-20(14-22(30)26(18,19)3)25(2)9-8-17(28)12-16(25)13-21(24)29;;/h15-22,24,28-30H,4-14H2,1-3H3,(H,27,31)(H,32,33,34);;1H2/q;+1;/p-1/t15-,16+,17-,18-,19+,20+,21-,22+,24+,25+,26-;;/m1../s1
InChI key
RDAJAQDLEFHVNR-NEMAEHQESA-M
Application
牛磺胆酸钠水合物用作原位制备消化酶的乳化剂。
Biochem/physiol Actions
牛磺胆酸是胆固醇分解代谢的主要终产物。在肠肝循环期间，胆汁牛磺胆酸被微生物转化为牛磺酸脱氧胆酸和脱氧胆酸。它们通过载体介导的过程被肝脏重吸收，并通过肝酶转化为牛磺胆酸。
Preparation Note
牛磺胆酸钠水合物在水中产生 50mg/ml 的澄清、无色溶液。
Other Notes
用于溶解未结合的胆红素
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
L R Schwarz et al.
European journal of biochemistry, 55(3), 617-623 (1975-07-15)
Binding and transport characteristics for uptake of taurocholic acid by isolated rat liver cells were studied. 1. An adsorption of taurocholate to the cell surface is terminated in less than 15 s. A Ks of 0.55 mM and a total
Subhashis Chakraborty et al.
Journal of colloid and interface science, 335(2), 242-249 (2009-05-01)
The effect of surfactants on the solubility of a new phosphate salt of carvedilol was investigated at different biorelevent pH to evaluate their solubilization capacity. Solutions of different classes of surfactants viz., anionic-sodium dodecyl sulfate (SDS) and sodium taurocholate (STC)
Martin Bluth et al.
Archives of surgery (Chicago, Ill. : 1960), 143(3), 227-233 (2008-03-19)
Blood leukocytes play a major role in mediating local and systemic inflammation during acute pancreatitis. We hypothesize that peripheral blood mononuclear cells (PBMCs) in circulation exhibit unique changes in gene expression and could provide a "reporter" function that reflects the
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| 86339-1G | 04061833040881 |
| 86339-25G | 04061833040898 |
| 86339-5G | 04061835541829 |