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I0516

胰岛素 溶液 来源于牛胰腺

BioReagent, 10 mg/mL insulin in 25  mM HEPES, pH 8.2, sterile-filtered, suitable for cell culture

别名:

Bovine insulin, Cell culture grade insulin

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关于此项目

化学文摘社编号:
11070-73-8
UNSPSC Code:
12352209
NACRES:
NA.77
MDL number:
MFCD00131380
Biological source:
bovine
Form:
solution
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biological source

bovine

Quality Level

400

sterility

sterile-filtered

product line

BioReagent

form

solution

concentration

10 mg/mL insulin in 25  mM HEPES, pH 8.2

technique(s)

cell culture | mammalian: suitable, single cell analysis: suitable

impurities

endotoxin, tested

pH

7.9-8.5

UniProt accession no.

P01317

shipped in

ambient

storage temp.

2-8°C

SMILES string

SC[C@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)CN)[C@H](CC)C)C(C)C)CCC(=O)O)CCC(=O)N)CS)C(=O)N[C@@H](C)C(=O)N[C@@H](CO)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CS)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](Cc4ccc(cc4)O)C(=O)N[

InChI

1S/2C97H151N25O34S4/c2*1-12-46(10)77(120-72(131)35-98)96(154)122-76(45(8)9)94(152)107-55(24-28-74(134)135)79(137)104-53(22-26-69(100)128)82(140)116-66(40-159)93(151)118-64(38-157)90(148)103-47(11)78(136)114-63(37-124)89(147)121-75(44(6)7)95(153)119-67(41-160)92(150)115-62(36-123)88(146)109-57(30-43(4)5)84(142)110-58(31-48-13-17-50(125)18-14-48)85(143)105-52(21-25-68(99)127)80(138)108-56(29-42(2)3)83(141)106-54(23-27-73(132)133)81(139)112-60(33-70(101)129)87(145)111-59(32-49-15-19-51(126)20-16-49)86(144)117-65(39-158)91(149)113-61(97(155)156)34-71(102)130/h2*13-20,42-47,52-67,75-77,123-126,157-160H,12,21-41,98H2,1-11H3,(H2,99,127)(H2,100,128)(H2,101,129)(H2,102,130)(H,103,148)(H,104,137)(H,105,143)(H,106,141)(H,107,152)(H,108,138)(H,109,146)(H,110,142)(H,111,145)(H,112,139)(H,113,149)(H,114,136)(H,115,150)(H,116,140)(H,117,144)(H,118,151)(H,119,153)(H,120,131)(H,121,147)(H,122,154)(H,132,133)(H,134,135)(H,155,156)/t2*46-,47-,52-,53-,54-,55-,56-,57-,58-,59-,60-,61-,62-,63-,64-,65-,66-,67-,75-,76-,77-/m00/s1

InChI key

XYPANFGXFLOTDK-CJLNJPJHSA-N

Gene Information

bovine ... INS(280829)
cow ... INS(280829)

Application

牛胰腺胰岛素溶液已用于：
  • 研究外源胰岛素对发育期肉牛血浆葡萄糖、胰岛素、胰岛素样生长因子 I（IGF-I）和孕酮（P4）浓度的影响
  • 利用原代人滋养层细胞和胎盘绒毛外植体研究妊娠并发症期间胎盘的胰岛素反应性
  • 研究胰岛素受体信号通路对新生小鼠海马神经元树突棘密度的影响

Biochem/physiol Actions

由胰岛β-细胞所产生的二链多肽激素。其分子量为~5800 Da。α链和β链是由两个链间二硫键所连接的。α链含有一个链间二硫键。胰岛素可调节细胞对葡萄糖、氨基酸和脂肪酸的摄取、利用和储存，并抑制糖原、蛋白质和脂肪的分解。
胰岛素是一种重要的降糖激素，它的不足会导致 2 型糖尿病患者出现高血糖。

Physical form

2-8 °C保存

存储类别

12 - Non Combustible Liquids

wgk

WGK 2

ppe

Eyeshields, Gloves

法规信息

低风险生物材料
兴奋剂肽类激素

此项目有

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number
SLCJ8080
SLCB9851
SLBZ8936
SLBX8457
SLBW8931

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货号GTIN
I0516-5ML04061838101051