产品名称
抗-β-微管蛋白III 兔抗, ~1 mg/mL, affinity isolated antibody, buffered aqueous solution
biological source
rabbit
Quality Level
conjugate
unconjugated
antibody form
affinity isolated antibody
antibody product type
primary antibodies
clone
polyclonal
form
buffered aqueous solution
mol wt
antigen ~50 kDa
species reactivity
human
concentration
~1 mg/mL
technique(s)
western blot: 1:500-1:1,000
UniProt accession no.
shipped in
dry ice
storage temp.
−20°C
target post-translational modification
unmodified
Gene Information
human ... TUBB3(10381)
mouse ... Tubb3(22152)
rat ... Tubb3(246118)
General description
微管是异二聚体蛋白，由α- 和β-微管蛋白组成。β-微管蛋白有多种不同的同种型。β-微管蛋白III是神经细胞分化以及静脉和淋巴管瓣的标志物。β-微管蛋白III表达的变化与成神经管细胞瘤有关
抗微管蛋白抗体可用于研究微管蛋白的定位。抗β微管蛋白III抗体具有人β-微管蛋白III特异性。
抗微管蛋白抗体可用于研究微管蛋白的定位。抗β微管蛋白III抗体具有人β-微管蛋白III特异性。
微管蛋白β 3 III类（TUBB3） 位于人类染色体 16q24.3。
Immunogen
对应人 β-微管蛋白 III 残基 151-165 的合成肽。
Application
抗 β-Tubulin III 抗体适用于流式细胞术 (1:200-1:500)、免疫组化 (1:100-1:200)、免疫印迹（约 50 kDa）和 免疫印迹(1:500-1:1,000)。
Biochem/physiol Actions
微管蛋白β3 III 类基因（TUBB3）中的错义突变影响神经元细胞的微管组织，并导致神经系统疾病。TUBB3 突变与导致发育中胎儿畸形的肾小管病变有关。
Physical form
溶剂为含有0.02％叠氮化钠的磷酸盐缓冲盐水。
Disclaimer
除非我们的产品目录或产品附带的其他公司文档另有说明，否则我们的产品仅供研究使用，不得用于任何其他目的，包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或任何类型的消费或应用于人类或动物。
Still not finding the right product?
存储类别
10 - Combustible liquids
wgk
nwg
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)
法规信息
常规特殊物品
低风险生物材料
此项目有
Sanaz Yahyanejad et al.
Oncotarget, 7(27), 41251-41264 (2016-05-18)
Glioblastoma multiforme (GBM) is the most common malignant brain tumor in adults. The current standard of care includes surgery followed by radiotherapy (RT) and chemotherapy with temozolomide (TMZ). Treatment often fails due to the radiation resistance and intrinsic or acquired
Jun Kang et al.
Cardiovascular pathology : the official journal of the Society for Cardiovascular Pathology, 15(4), 218-221 (2006-07-18)
Lymphatic and venous valves are essential for unidirectional circulation; however, no specific marker has been described for these valves. Here, we show that TuJ1 (class III beta-tubulin) is expressed strongly in valve endothelium but not in nonvalvular endothelium lining of
Seungkoo Lee et al.
European journal of cell biology, 84(2-3), 453-459 (2005-04-12)
Follicular dendritic cells (FDCs) play central roles in the B cell survival, proliferation, and differentiation into memory cells. Here, we show that TuJ1 (class III beta-tubulin) is expressed strongly in FDCs of human lymphoid tissue. TuJ1 has been a marker
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| T3952-100UG | 04061838026880 |