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A0781

Aphidicolin from Nigrospora sphaerica

≥98% (HPLC), DNA polymerase inhibitor, powder

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关于此项目

经验公式（希尔记法）:
C20H34O4
化学文摘社编号:
38966-21-1
分子量:
338.48
NACRES:
NA.77
PubChem Substance ID:
57653817
UNSPSC Code:
12352200
MDL number:
MFCD00083214
Beilstein/REAXYS Number:
4689958
Assay:
≥98% (HPLC)
Form:
powder
Quality level:
300
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产品名称

Aphidicolin from Nigrospora sphaerica, ≥98% (HPLC), powder

Quality Level

300

assay

≥98% (HPLC)

form

powder

optical activity

[α]27/D +12°, c = 1 in methanol(lit.)

color

white

mp

227-233 °C (lit.)

solubility

ethanol: 1 mg/mL (stable at least a week at 4°C.), DMSO: 10 mg/mL (stable at least six weeks at −20°C.), methanol: 10 mg/mL, H2O: insoluble

antibiotic activity spectrum

neoplastics, viruses

mode of action

DNA synthesis | interferes

storage temp.

2-8°C

SMILES string

[H][C@@]12CC[C@@]3([H])[C@](C)(CO)[C@H](O)CC[C@]3(C)[C@]14CC[C@](O)(CO)[C@]([H])(C2)C4

InChI

1S/C20H34O4/c1-17(11-21)15-4-3-13-9-14-10-19(13,7-8-20(14,24)12-22)18(15,2)6-5-16(17)23/h13-16,21-24H,3-12H2,1-2H3/t13-,14+,15-,16+,17-,18-,19-,20-/m0/s1

InChI key

NOFOAYPPHIUXJR-APNQCZIXSA-N

Gene Information

human ... POLA1(5422), POLD1(5424), POLG(5428)

Biochem/physiol Actions

Aphidicolin is an antibiotic, a potent antiviral and antimitotic agent and DNA polymerase inhibitor.

Features and Benefits

This compound is a featured product for Apoptosis research. Click here to discover more featured Apoptosis products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.

Disclaimer

Estimated shelf-life is two years. For optimal stability, it should be protected from light and stored desiccated.

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

法规信息

涉药品监管产品

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历史批次信息供参考:

分析证书(COA)

Lot/Batch Number
14100608
077M4009V
068M4008V
069M4047V
029M4023V

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商品

Discover Bioactive Small Molecules for Cell Cycle

Cell cycle phases (G1, S, G2, M) regulate cell growth, DNA replication, and division in proliferating cells.

Bioactive Molecules for Apoptosis

Apoptosis regulation involves multiple pathways and molecules for cellular homeostasis.

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