A2754
腺苷-5′-二磷酸 钠盐
≥95% (HPLC), bacterial, powder
别名:
ADP钠盐, ADP
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关于此项目
经验公式（希尔记法）:
C10H15N5O10P2
化学文摘社编号:
分子量:
427.20
UNSPSC Code:
41106305
eCl@ss:
32160414
PubChem Substance ID:
NACRES:
NA.51
Assay:
≥95% (HPLC)
Biological source:
bacterial
Form:
powder
Solubility:
water: 50 mg/mL, clear to hazy, colorless
Storage temp.:
−20°C
产品名称
腺苷-5′-二磷酸 钠盐, bacterial, ≥95% (HPLC)
biological source
bacterial
Quality Level
assay
≥95% (HPLC)
form
powder
solubility
water: 50 mg/mL, clear to hazy, colorless
storage temp.
−20°C
SMILES string
[Na].Nc1ncnc2n(cnc12)C3OC(COP(O)(=O)OP(O)(O)=O)C(O)C3O
InChI
1S/C10H15N5O10P2/c11-8-5-9(13-2-12-8)15(3-14-5)10-7(17)6(16)4(24-10)1-23-27(21,22)25-26(18,19)20/h2-4,6-7,10,16-17H,1H2,(H,21,22)(H2,11,12,13)(H2,18,19,20)/t4-,6-,7-,10-/m1/s1
InChI key
XTWYTFMLZFPYCI-KQYNXXCUSA-N
Gene Information
human ... HSP90AA1(3320), P2RY1(5028)
General description
5′-二磷酸腺苷（ADP）是一种通过 FOF1-ATP 合酶转化为 ATP 而参与能量储存和核酸代谢的腺嘌呤核苷酸。ADP也可通过单磷酸腺苷酸（AMP）的腺苷酸激酶催化反应得到。ADP是一种血小板激动剂，由血小板致密颗粒分泌。它通过其与ADP受体P2Y1和P2Y12的相互作用影响血小板活化。ADP在通过ecto-ADP酶转化为腺苷后，通过腺苷受体抑制血小板活化。
Application
5′-二磷酸腺苷钠盐已用作：
- 血小板聚集的阳性对照，用聚焦仪分析纯化解聚素的抗血小板活性。
- 制备原液以进行线粒体应激实验。
- 流式细胞术分析中的阳性对照品，用于研究五聚体C反应蛋白（pCRP）和单体CRP（mCRP）对血小板CD62p（P-选择素）表达的影响。
- 血小板激动剂，刺激血小板聚集。
存储类别
11 - Combustible Solids
flash_point_f
Not applicable
flash_point_c
Not applicable
实验方案
HILIC separation is an alternative that permits sensitive MS detection and without the use of ion-pair reagents.
ZIC®-cHILIC is a densely bonded zwitterionic stationary phase with phosphorylcholine functional groups covalently attached to silica.
Klaus H Nielsen et al.
RNA (New York, N.Y.), 15(1), 67-75 (2008-11-27)
The exon junction complex (EJC) is deposited onto spliced mRNAs and is involved in many aspects of mRNA function. We have recently reconstituted and solved the crystal structure of the EJC core made of MAGOH, Y14, the most conserved portion
Richard C Jin et al.
Circulation, 123(18), 1963-1973 (2011-04-27)
Glutathione peroxidase-3 (GPx-3) is a selenocysteine-containing plasma protein that scavenges reactive oxygen species in the extracellular compartment. A deficiency of this enzyme has been associated with platelet-dependent thrombosis, and a promoter haplotype with reduced function has been associated with stroke
Tsui-Fen Chou et al.
Journal of molecular biology, 426(15), 2886-2899 (2014-06-01)
The p97 AAA (ATPase associated with diverse cellular activities), also called VCP (valosin-containing protein), is an important therapeutic target for cancer and neurodegenerative diseases. p97 forms a hexamer composed of two AAA domains (D1 and D2) that form two stacked
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| A2754-100MG | 04061835540556 |
| A2754-1G | 04061835488773 |
| A2754-500MG | 04061835517602 |
| A2754-5X1G | 04061835553167 |