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关于此项目
经验公式（希尔记法）:
C5H5N5
化学文摘社编号:
分子量:
135.13
NACRES:
NA.51
PubChem Substance ID:
UNSPSC Code:
41106305
EC Number:
207-197-4
MDL number:
Assay:
≥99%
Biological source:
synthetic
Form:
powder
Storage temp.:
2-8°C
产品名称
2-氨基嘌呤, ≥99%
biological source
synthetic
assay
≥99%
form
powder
mp
280-282 °C (lit.)
storage temp.
2-8°C
SMILES string
Nc1ncc2[nH]cnc2n1
InChI
1S/C5H5N5/c6-5-7-1-3-4(10-5)9-2-8-3/h1-2H,(H3,6,7,8,9,10)
InChI key
MWBWWFOAEOYUST-UHFFFAOYSA-N
Application
αα2-氨基嘌呤已被用于抑制骨关节炎（OA）软骨细胞的真核起始因子2（eIF2）-磷酸化。
2-氨基嘌呤（2-AP）可用于双链RNA依赖性蛋白激酶、蛋白激酶R（PKR）的特异性抑制。
Biochem/physiol Actions
2-氨基嘌呤（2AP）是一种鸟苷和腺苷的类似物，可以与胞嘧啶和胸腺嘧啶碱基配对。它可用作核酸结构和动力学分析的荧光探针。2-氨基嘌呤（2-AP）可抑制双链RNA依赖性蛋白激酶蛋白激酶R（PKR）。
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signalword
Warning
hcodes
Hazard Classifications
Acute Tox. 4 Oral
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
Endoplasmic reticulum stress induces the expression of COX-2 through activation of eIF2alpha, p38-MAPK and NF-kappaB in advanced glycation end products stimulated human chondrocytes
Rasheed Z and HaqqiTM
Biochimica et Biophysica Acta - Molecular Cell Research, 1823(12), 2179-2189 (2012)
2-Aminopurine fluorescence quenching and lifetimes: role of base stacking
Jean JM and Hall KB
Proceedings of the National Academy of Sciences of the USA, 98(1), 37-41 (2001)
Danqing Xin et al.
Brain, behavior, and immunity, 73, 222-234 (2018-05-12)
We previously reported that l-Cysteine, an H2S donor, significantly alleviated brain injury after hypoxia-ischemic (HI) injury in neonatal mice. However, the mechanisms underlying this neuroprotective effect of l-Cysteine against HI insult remain unknown. In the present study, we tested the
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| A3509-250MG | 04061833361016 |
| A3509-500MG | 04061833045367 |
| A3509-100MG | 04061833045350 |
| A3509-1G | 04061826688328 |