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Merck
CN

A4599

L -精氨酸 单盐酸盐

别名:

(S)-(+)-2-氨基-5-[(氨基亚甲基)氨基]戊酸 单盐酸盐, (S)-(+)-精氨酸 盐酸盐

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关于此项目

经验公式(希尔记法):
C6H14N4O2 · HCl
化学文摘社编号:
分子量:
210.66
EC Number:
214-275-1
UNSPSC Code:
12352209
NACRES:
NA.26
Beilstein/REAXYS Number:
3631658
MDL number:
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biological source

non-animal source

Quality Level

assay

≥98.5%

form

crystalline powder

technique(s)

cell culture | mammalian: suitable

impurities

endotoxin, heavy metals, residual solvents, tested

solubility

H2O: 100 mg/mL

density

1.42 g/cm3 at 20 °C

anion traces

chloride (Cl-): 16.58-17.00%, sulfate (SO42-): ≤0.020%

cation traces

As: ≤1.0 ppm, NH4+: ≤0.02%, heavy metals: ≤10 ppm

application(s)

pharmaceutical (small molecule)

foreign activity

cytotoxicity, tested

General description

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我们用于生物制药加工的SAFC® 系列优质原料经过严格的质量控制流程,配合记录文件和技术专长帮助我们的客户达到M-Clarity Program规定的要求。

M-Clarity Program

我们全面的上游工艺化学品系列不仅为生物制药生产商提供生产传统和创新治疗药物所需的优质原料,而且帮助他们更快地将产品投放市场并简化监管问题。请相信我们能够为您带来透明供应链的和可靠的全球采购能力,以最佳的法规支持和服务简化您的产品认证。

Application

L-精氨酸是一种非必需氨基酸。 它被作为细胞培养基成分用于治疗性重组蛋白和单克隆抗体的商业化生物制造。L-精氨酸单盐酸盐是一种改良型L-精氨酸,具有更好的溶解度。

Biochem/physiol Actions

一氧化氮合成酶的底物,可以转化为瓜氨酸和一氧化氮 (NO)。通过与一氧化氮相关的机理诱导胰岛素释放。

Legal Information

SAFC is a registered trademark of Merck KGaA, Darmstadt, Germany


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存储类别

11 - Combustible Solids

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves



历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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The Biochemical journal, 462(3), 513-523 (2014-07-02)
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N E Paul et al.
Bio-medical materials and engineering, 25(3), 289-297 (2015-09-26)
Adipose tissue engineering is a promising solution for the reconstruction of soft tissue defects. An insufficient neovascularisation within the scaffolds that leads to necrosis and tissue loss is still a major shortcoming of current tissue engineering attempts. Biomaterials, which release
Carolina Di Somma et al.
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The aim of the study is to clarify the relationship between adipose tissue dysfunction, metabolic profile and growth hormone (GH)/insulin-like growth factor (IGF)-I secretion in healthy adult subjects. We investigated the metabolic profile in a cohort of 231 consecutive healthy



全球贸易项目编号

货号GTIN
A4599-100G04061834352471
A4599-1KG04061833374771
A4599-10KG04061834410904
A4599-25KG04061834410911
A4599-A150X04061834178781
A4599-A150XCONF04061834178798