A5486
偶氮甲烷
13.4 M, ≥98%
别名:
AOM
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线性分子式:
CH3N=N(→O)CH3
化学文摘社编号:
分子量:
74.08
NACRES:
NA.25
PubChem Substance ID:
UNSPSC Code:
12352124
MDL number:
Assay:
≥98%
Form:
liquid
Quality level:
Storage condition:
(Keep container tightly closed in a dry and well-ventilated place.)
Quality Level
assay
≥98%
form
liquid
composition
methylene chloride, ≤1%
storage condition
(Keep container tightly closed in a dry and well-ventilated place.)
concentration
13.4 M
color
colorless
bp
97-99 °C (lit.)
density
0.991 g/mL at 25 °C (lit.)
application(s)
genomic analysis
storage temp.
−20°C
SMILES string
C\N=[N+](/C)[O-]
InChI
1S/C2H6N2O/c1-3-4(2)5/h1-2H3/b4-3+
InChI key
DGAKHGXRMXWHBX-ONEGZZNKSA-N
General description
偶氮甲烷（AOM）是一种功能强大的实验室化学品，用于研究癌症，特别是结肠癌的发生、进展和预防。它可用作引发肿瘤形成的致癌物和导致DNA特异性改变的基因突变剂。
Application
氧化偶氮甲烷（AOM），一种基因突变剂，可与硫酸葡聚糖钠（DSS）一起用于在实验室动物中创建癌症模型，从而用于研究癌症进展和化学预防的机制。
Biochem/physiol Actions
诱导DNA中O6-甲基鸟嘌呤加合物的致癌物导致G→A转变。 在实验动物的结肠中诱导肿瘤生成，并用于研究癌症进展和化学预防的机制。
Features and Benefits
用途广泛，适用于各种实验室和研究应用。
signalword
Danger
hcodes
Hazard Classifications
Acute Tox. 2 Oral - Carc. 1B - Eye Irrit. 2 - Flam. Liq. 3 - Skin Irrit. 2
存储类别
3 - Flammable liquids
wgk
WGK 3
flash_point_f
75.2 °F
flash_point_c
24 °C
法规信息
危险化学品
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全球贸易项目编号
| 货号 | GTIN |
|---|---|
| A5486-100MG | 04061837839597 |
| A5486-25MG | 04061837839603 |