主要文件

查看所有文档

A5585

5-（N-甲基-N-异丁基）阿米洛利

Name: 5-（N-甲基-N-异丁基）阿米洛利
Brand: SIGMA

≥98% (TLC), powder

别名:

MIA

登录查看组织和合同定价。

选择尺寸

变更视图

关于此项目

经验公式（希尔记法）:

C₁₁H₁₈ClN₇O

化学文摘社编号:

96861-65-3

分子量:

299.76

NACRES:

NA.77

PubChem Substance ID:

24278228

UNSPSC Code:

12352200

MDL number:

MFCD00078567

Assay:

≥98% (TLC)

Form:

powder

Quality level:

200

技术服务

需要帮助？我们经验丰富的科学家团队随时乐意为您服务。

让我们为您提供帮助

属性

Quality Level

200

assay

≥98% (TLC)

form

powder

mp

200-201 °C

solubility

methanol: 9.80-10.20 mg/mL, clear, pale yellow to yellow

storage temp.

2-8°C

SMILES string

CC(C)CN(C)c1nc(N)c(nc1Cl)C(=O)NC(N)=N

InChI

1S/C11H18ClN7O/c1-5(2)4-19(3)9-7(12)16-6(8(13)17-9)10(20)18-11(14)15/h5H,4H2,1-3H3,(H2,13,17)(H4,14,15,18,20)

InChI key

RVIUMPLAOXSSGN-UHFFFAOYSA-N

Gene Information

human ... SCNN1A(6337), SCNN1B(6338), SCNN1D(6339), SCNN1G(6340)
mouse ... Scnn1a(20276), Scnn1b(20277), Scnn1d(140501), Scnn1g(20278)
rat ... Scnn1a(25122), Scnn1b(24767), Scnn1g(24768)

说明

Application

5-（N-甲基-N-异丁基）阿米洛利是Na⁺/H⁺反向转运的有效阻滞剂。 5-（N-甲基-N-异丁基）阿米洛利已用于研究对酸中毒的早期细胞反应。

Biochem/physiol Actions

Na⁺/H⁺反向转运的有效阻滞剂。可能的抗肿瘤药物。

pictograms

GHS07

signalword

Warning

hcodes

H315,H319,H335

pcodes

P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

没有发现合适的版本？

如果您需要特殊版本，可通过批号或批次号查找具体证书。

搜索COA

已有该产品？

在文件库中查找您最近购买产品的文档。

访问文档库

Role of Na(+)/H(+) exchanger during ischemia and preconditioning in the isolated rat heart.

X H Xiao et al.

Circulation research, 85(8), 723-730 (1999-10-16)

The role of the Na(+)/H(+) exchanger in ischemia, reperfusion, and preconditioning was investigated in isolated perfused rat hearts. Contractile function, [Na(+)](i), and pH(i) were measured; ischemic damage was assessed by the recovery of developed pressure (DP) on reperfusion. After 30

Identification and expression of the Na+/H+ exchanger in mammalian cerebrovascular and choroidal tissues: characterization by amiloride-sensitive [3H]MIA binding and RT-PCR analysis.

R N Kalaria et al.

Brain research. Molecular brain research, 58(1-2), 178-187 (1998-08-01)

We report the initial characterization of [3H]5-(N-methyl-N-isobutyl)amiloride (MIA) binding to the Na+/H+ exchanger (NHE) and expression of its gene in mammalian cerebrovascular, choroidal and neocortical tissues. [3H]MIA bound reversibly to particulate fractions of rat, pig and human cerebral microvessels, choroid

Analysis of 13 cell types reveals evidence for the expression of numerous novel primate- and tissue-specific microRNAs.

Eric Londin et al.

Proceedings of the National Academy of Sciences of the United States of America, 112(10), E1106-E1115 (2015-02-26)

Two decades after the discovery of the first animal microRNA (miRNA), the number of miRNAs in animal genomes remains a vexing question. Here, we report findings from analyzing 1,323 short RNA sequencing samples (RNA-seq) from 13 different human tissue types.

查看所有相关文献

全球贸易项目编号

货号	GTIN
A5585-25MG	04061832569109
A5585-100MG	04061832269023