A6140
氨苄西林 三水合物
900-1050 μg/mg anhydrous basis (HPLC)
别名:
氨苄青霉素
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关于此项目
经验公式（希尔记法）:
C16H19N3O4S · 3H2O
化学文摘社编号:
分子量:
403.45
UNSPSC Code:
51281703
NACRES:
NA.85
PubChem Substance ID:
EC Number:
200-709-7
Beilstein/REAXYS Number:
5399534
MDL number:
Quality Level
form
powder or crystals
concentration
900-1050 μg/mg (anhydrous, HPLC)
mp
198-200 °C (dec.) (lit.)
antibiotic activity spectrum
Gram-negative bacteria, Gram-positive bacteria
mode of action
cell wall synthesis | interferes
storage temp.
2-8°C
SMILES string
O.O.O.CC1(C)S[C@@H]2[C@H](NC(=O)[C@H](N)c3ccccc3)C(=O)N2[C@H]1C(O)=O
InChI
1S/C16H19N3O4S.3H2O/c1-16(2)11(15(22)23)19-13(21)10(14(19)24-16)18-12(20)9(17)8-6-4-3-5-7-8;;;/h3-7,9-11,14H,17H2,1-2H3,(H,18,20)(H,22,23);3*1H2/t9-,10-,11+,14-;;;/m1.../s1
InChI key
RXDALBZNGVATNY-CWLIKTDRSA-N
General description
化学结构:β-内酰胺
Application
氨苄西林三水合物通常用于选择突变和转化细胞中的氨苄西林抗性。
Biochem/physiol Actions
一种具有连接到青霉素结构上的氨基侧链的 β-内酰胺抗生素。通过灭活细菌细胞膜内表面的转肽酶而抑制细菌细胞壁合成（肽聚糖交联）的青霉素衍生物。仅对生长中的大肠埃希菌具有杀菌作用。耐药方式：氨苄西林的 β-内酰胺环被 β-内酰胺酶裂解。抗菌谱：革兰阴性菌和革兰阳性菌。
Other Notes
保存于密闭容器内，置于干燥通风处。
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signalword
Danger
hcodes
Hazard Classifications
Eye Irrit. 2 - Resp. Sens. 1 - Skin Irrit. 2 - Skin Sens. 1 - STOT SE 3
target_organs
Respiratory system
存储类别
11 - Combustible Solids
wgk
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Faceshields, Gloves
法规信息
涉药品监管产品
此项目有
H J Nelis et al.
Antimicrobial agents and chemotherapy, 36(8), 1606-1610 (1992-08-01)
The determination of ampicillin in plasma and serum by reversed-phase high-performance liquid chromatography with UV detection suffers from poor selectivity and sensitivity. Currently, the most common approach to overcoming these problems consists of improving the compound's detectability via pre- or
Ramendra K Singh et al.
European journal of medicinal chemistry, 45(3), 1078-1086 (2009-12-26)
Curcumin bioconjugates, viz. di-O-tryptophanylphenylalanine curcumin (2), di-O-decanoyl curcumin (3), di-O-pamitoyl curcumin (4), di-O-bis-(gamma,gamma)folyl curcumin (6), C(4)-ethyl-O-gamma-folyl curcumin (8) and 4-O-ethyl-O-gamma-folyl curcumin (10) have been synthesized and tested for their antibacterial and antiviral activities. The conjugates 2, 3, 4, 6 and
Sherif A F Rostom et al.
Bioorganic & medicinal chemistry, 17(2), 882-895 (2008-12-17)
The synthesis of two groups of structure hybrids comprising basically the antipyrine moiety attached to either polysubstituted thiazole or 2,5-disubstituted-1,3,4-thiadiazole counterparts through various linkages is described. Twelve out of the newly synthesized compounds were evaluated for their anti-inflammatory activity using
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| A6140-5G | 04061833377321 |
| A6140-100G | 04061834400394 |
| A6140-25G | 04061833377291 |