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Merck
CN

A7223

白蛋白 人

recombinant, expressed in Pichia pastoris, 5% in aqueous buffer, ≥90% (SDS-PAGE)

别名:

Albagen, rHSA

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关于此项目

经验公式(希尔记法):
C2936H4624N786O889S41
化学文摘社编号:
分子量:
66471.53
UNSPSC Code:
12352202
NACRES:
NA.25
MDL number:
Biological source:
human
Assay:
≥90% (SDS-PAGE)
Form:
solution
Technique(s):
cell culture | mammalian: suitable
Concentration:
5% in aqueous buffer
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biological source

human

Quality Level

recombinant

expressed in Pichia pastoris

assay

≥90% (SDS-PAGE)

form

solution

mol wt

monomer ~67 kDa

concentration

5% in aqueous buffer

technique(s)

cell culture | mammalian: suitable

UniProt accession no.

shipped in

wet ice

storage temp.

2-8°C

SMILES string

FC(F)(F)C(F)(F)C(F)(F)F

InChI

1S/C3F8/c4-1(5,2(6,7)8)3(9,10)11

InChI key

QYSGYZVSCZSLHT-UHFFFAOYSA-N

Gene Information

human ... ALB(213)

General description

Asp N末端缺失的重组构建体。X射线晶体学证实了其与天然白蛋白的结构等同性。Asp N末端是主要的Cu2+和Ni2+ 螯合位点;其缺失消除了一个重要的抗原决定簇,让蛋白质具有低过敏源性。还可在Cys34处阻断,改善稳定性、单体含量和均质性。

Application

该重组变异建议用于:吸收、分散、代谢和排泄(ADME)药理学研究;细胞培养;药物递送研究;细胞冻存。

Biochem/physiol Actions

白蛋白是可见于动物体液和组织及部分植物种子的一类可溶性单体蛋白。 血清白蛋白可作为类固醇、脂肪酸和甲状腺激素的载体蛋白。 血清白蛋白在调节血液的胶体渗透压方面也至关重要。

Physical form

磷酸盐缓冲盐水溶液,含有4 mM辛酸钠和 4 mM N-乙酰色氨酸。

Other Notes

更多信息参见人血清白蛋白

Legal Information

Albagen is a trademark of Albumin Therapeutics, LLC.


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存储类别

12 - Non Combustible Liquids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

法规信息

常规特殊物品

此项目有



历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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全球贸易项目编号

货号GTIN
A7223-1G04061833383834