A7646
三磷酸腺苷双磷酸酶 来源于马铃薯
ATPase ≥60 units/mg protein, lyophilized powder (partially purified)
别名:
腺苷5′-三磷酸酶, 腺苷5′-二磷酸酶
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关于此项目
化学文摘社编号:
UNSPSC Code:
12352204
NACRES:
NA.54
EC Number:
232-569-8
MDL number:
Biological source:
potato
biological source
potato
Quality Level
type
Grade III
form
lyophilized powder (partially purified)
ATPase activity
≥60 units/mg protein
mol wt
~49 kDa by gel filtration
composition
Protein, 30-60%
solubility
H2O: soluble 10 mg/mL, slightly hazy
application(s)
diagnostic assay manufacturing
foreign activity
Acid Phosphatase ≤5% of base activity
storage temp.
−20°C
Application
三磷酸核苷和二磷酸核苷的水解酶。对于有机二磷酸和三磷酸的水解，最适 pH 为 6，对于无机底物，最适 pH 为 5.1 。该酶已被用于评估 ATP 参与肠道固有层 Th17 细胞分化的可能性。
不同种类的马铃薯(S. tuberosum)中存在至少2种同工酶：一种的ATP酶/ADP酶比例较高(∼10)和另一种较低(∼1)。
反应：ATP → ADP+Pi → AMP+2Pi。
反应：ATP → ADP+Pi → AMP+2Pi。
Biochem/physiol Actions
在所有的真核生物和一些原核生物中都存在着这种酶。来自马铃薯的三磷酸腺苷双磷酸酶，对生长发育具有至关重要的调节作用。在神经刺激后，作为神经递质参与突触 ATP 的失活，并抑制 ADP 诱导的血小板聚集以防止血栓形成。活性需要二价金属离子，钙离子在 5 mm 时活性最好，发现蛋白分子量约为 45 kDa。
Packaging
按 atp 酶单位销售
Analysis Note
含量≤5% 酸性磷酸酶。
Other Notes
在pH 6.5、30℃条件下，一单位酶每分钟可从ATP或ADP释放1.0 μmM无机磷酸盐。
高比率和低比率同工酶混合物。
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signalword
Danger
hcodes
pcodes
Hazard Classifications
Resp. Sens. 1
存储类别
11 - Combustible Solids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
法规信息
低风险生物材料
此项目有
Properties of Two Apyrases from Solanum tuberosum
Kettlun, A. et al.
Phytochemistry, 21(3), 551-558 (1982)
Mathieu F Chevalier et al.
Blood, 121(1), 29-37 (2012-10-09)
Natural regulatory T cells (Tregs) participate in responses to various chronic infections including HIV. HIV infection is associated with a progressive CD4 lymphopenia and defective HIV-specific CD8 responses known to play a key role in the control of viral replication.
Mardi C Boer et al.
European journal of immunology, 43(7), 1925-1932 (2013-04-23)
Regulatory T (Treg) cells can balance normal tissue homeostasis by limiting inflammatory tissue damage, e.g. during pathogen infection, but on the other hand can also limit protective immunity induced during natural infection or following vaccination. Because most studies have focused
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| A7646-100UN | 04061832754642 |
| A7646-200UN | 04061832754659 |
| A7646-5KU | 04061833385999 |
| A7646-1KU | 04061833385968 |
| A7646-2KU | 04061833385982 |
| A7646-500UN | 04061832754666 |