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Merck
CN

A8185

丙氨酸-谷氨酰胺

BioReagent, suitable for cell culture, suitable for insect cell culture

别名:

丙氨酰谷氨酰胺, 丙谷二肽

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关于此项目

经验公式(希尔记法):
C8H15N3O4
化学文摘社编号:
分子量:
217.22
UNSPSC Code:
12352209
PubChem Substance ID:
NACRES:
NA.75
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product line

BioReagent

Quality Level

assay

≥98% (HPLC)

form

powder

technique(s)

cell culture | insect: suitable, cell culture | mammalian: suitable

color

white to off-white

storage temp.

room temp

SMILES string

NC(CC[C@H](NC([C@@H](N)C)=O)C(O)=O)=O

InChI

1S/C8H15N3O4/c1-4(9)7(13)11-5(8(14)15)2-3-6(10)12/h4-5H,2-3,9H2,1H3,(H2,10,12)(H,11,13)(H,14,15)/t4-,5-/m0/s1

InChI key

HJCMDXDYPOUFDY-WHFBIAKZSA-N

Application

丙氨酰谷氨酰胺可用于:
  • 用作NeuralQ培养基的补充剂
  • 用作视网膜细胞系生长培养基和培育培养基(IM)的组分
  • 分别应用于视网膜细胞系的实验性治疗

Biochem/physiol Actions

丙氨酰谷氨酰胺(Ala-Gln)是一种在哺乳动物细胞培养基中用于替代谷氨酰胺的二肽,因为溶液中谷氨酰胺的不稳定性和分解产物氨的形成可对培养细胞产生有害影响。丙氨酰谷氨酰胺对热力灭菌稳定,比谷氨酰胺具有更低的氨化性,有助于发挥其作为培养基成分的优势。利用丙氨酰谷氨酰胺研究体外多形核白细胞和髓过氧化物酶的活性。

Analysis Note

该产品经过细胞培养测试(0.5mg/ml)和昆虫细胞培养测试(0.2mg/ml)。它适用于2-10mM的细胞培养和昆虫细胞培养应用。

Legal Information

NeuralQ is a trademark of GlobalStem


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存储类别

11 - Combustible Solids

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)



历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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实验方案

产生人诱导多能干细胞(iPSC)的干细胞重编程实验方案,包括基于病毒和非病毒RNA的方法。

Stem cell reprogramming protocols to generate human induced pluripotent stem cells (iPSCs) including viral and non-viral RNA based methods.

商品

PLTMax® Human Platelet Lysate (hPL) is a superior serum-free and xeno-free media supplement alternative to fetal bovine serum (FBS) for human mesenchymal stem cell (MSC) cultures.


Vinicius Fernandes Cruzat et al.
Nutrition (Burbank, Los Angeles County, Calif.), 25(4), 428-435 (2008-12-06)
We investigated the effect of supplementation with the dipeptide L-alanyl-L-glutamine (DIP) and a solution containing L-glutamine and L-alanine, both in the free form, on the plasma and tissue concentrations of glutamine, glutamate, and glutathione (GSH) in rats subjected to long-duration
A high-throughput assay for mRNA silencing in primary cortical neurons in vitro with oligonucleotide therapeutics
Alterman JF, et al.
Bio-protocol, 7(16) (2017)
The adaptation of BHK cells to a non-ammoniagenic glutamate-based culture medium
Christie A, et al.
Biotechnology and Bioengineering, 64(3), 298-309 (1999)



全球贸易项目编号

货号GTIN
A8185-1KG04061833391273
A8185-100G04061833391266
A8185-5G04061835568093