A8949
L-天冬氨酸
≥99% (HPLC), BioXtra
别名:
(S)-(+)-氨基琥珀酸, (S)-氨基丁二酸
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关于此项目
线性分子式:
HO2CCH2CH(NH2)CO2H
化学文摘社编号:
分子量:
133.10
NACRES:
NA.26
PubChem Substance ID:
eCl@ss:
32160406
UNSPSC Code:
12352209
EC Number:
200-291-6
MDL number:
Beilstein/REAXYS Number:
1723530
产品名称
L-天冬氨酸, BioXtra, ≥99% (HPLC)
product line
BioXtra
Quality Level
assay
≥99% (HPLC)
form
powder
impurities
≤0.0005% Phosphorus (P), ≤0.1% Insoluble matter
ign. residue
≤0.1%
color
white to off-white
mp
>300 °C (dec.) (lit.)
solubility
1 M HCl: 0.5 M, clear, colorless
anion traces
chloride (Cl-): ≤0.05%, sulfate (SO42-): ≤0.05%
cation traces
Al: ≤0.0005%, Ca: ≤0.001%, Cu: ≤0.0005%, Fe: ≤0.0005%, K: ≤0.005%, Mg: ≤0.0005%, NH4+: ≤0.05%, Na: ≤0.005%, Pb: ≤0.001%, Zn: ≤0.0005%
SMILES string
N[C@@H](CC(O)=O)C(O)=O
InChI
1S/C4H7NO4/c5-2(4(8)9)1-3(6)7/h2H,1,5H2,(H,6,7)(H,8,9)/t2-/m0/s1
InChI key
CKLJMWTZIZZHCS-REOHCLBHSA-N
Gene Information
human ... CA1(759), CA2(760)
rat ... Grin2a(24409)
Application
- 代谢组学分析发现作为急性心肌梗死生物标志物的差异代谢物。：研究发现了参与急性心肌梗塞期间代谢途径的关键代谢物，包括L-天门冬氨酸。这项研究加深了人们对心脏病发作时生化变化的了解，有可能产生更好的诊断标志物（Zhou et al., 2024）。
Biochem/physiol Actions
L-天冬氨酸是天然蛋白原氨基酸，其可用于细胞培养基的配制，以及蛋白质和多肽合成系统和实验。L-天冬氨酸，一种 NMDA 受体激动剂和非特异性谷氨酸受体激动剂，用于鉴定 NMDA 受体，以及和研究其作用机制。
快速兴奋突触的主要神经递质。
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存储类别
11 - Combustible Solids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
Irena Roci et al.
Cell reports, 26(7), 1691-1700 (2019-02-14)
Alterations in cell-cycle regulation and cellular metabolism are associated with cancer transformation, and enzymes active in the committed cell-cycle phase may represent vulnerabilities of cancer cells. Here, we map metabolic events in the G1 and SG2M phases by combining cell
Johnny Bonnardel et al.
Immunity, 51(4), 638-654 (2019-09-29)
Macrophages are strongly adapted to their tissue of residence. Yet, little is known about the cell-cell interactions that imprint the tissue-specific identities of macrophages in their respective niches. Using conditional depletion of liver Kupffer cells, we traced the developmental stages
Ann-Louise Johansson et al.
Proceedings of the National Academy of Sciences of the United States of America, 110(22), 8912-8917 (2013-05-16)
Proton transfer across biological membranes underpins central processes in biological systems, such as energy conservation and transport of ions and molecules. In the membrane proteins involved in these processes, proton transfer takes place through specific pathways connecting the two sides
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| A8949-100G | 04061833400975 |
| A8949-25G | 04061833400999 |
| A8949-10MG | 04061833617052 |
| A8949-1G | 04061833400982 |