B169
BRL 37344 钠盐 水合物
≥98% (HPLC), β3-adrenergic receptor agonist, solid
别名:
(±)-(R*,R*)- [4- [2- [ [2-（3-氯苯基）-2-羟乙基] 氨基] 丙基] 苯氧基] 乙酸钠 水合物, BRL 37344A
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关于此项目
经验公式（希尔记法）:
C19H21ClNNaO4 · xH2O
化学文摘社编号:
分子量:
385.82 (anhydrous basis)
MDL number:
UNSPSC Code:
12352200
PubChem Substance ID:
NACRES:
NA.77
产品名称
BRL 37344 钠盐 水合物, solid
assay
≥98% (HPLC)
Quality Level
form
solid
color
white
solubility
DMSO: 18 mg/mL, clear (warmed)
SMILES string
O.[Na+].C[C@H](Cc1ccc(OCC([O-])=O)cc1)NC[C@H](O)c2cccc(Cl)c2
InChI
1S/C19H22ClNO4.Na.H2O/c1-13(21-11-18(22)15-3-2-4-16(20)10-15)9-14-5-7-17(8-6-14)25-12-19(23)24;;/h2-8,10,13,18,21-22H,9,11-12H2,1H3,(H,23,24);;1H2/q;+1;/p-1/t13-,18+;;/m1../s1
InChI key
YTPAKDODIXRQTF-BNTHFPBMSA-M
Gene Information
human ... ADRB3(155)
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
M A Oriowo et al.
The Journal of pharmacology and experimental therapeutics, 277(1), 22-27 (1996-04-01)
The stimulation by BRL 37344 of lipolysis in rat adipose tissues, and of relaxation of the rat distal colon, is mediated by the beta-3 adrenoceptor. The stereochemical requirements of the beta-3 adrenoceptor are poorly understood. The activities of the four
S Tsujii et al.
Physiology & behavior, 63(4), 723-728 (1998-04-02)
This study evaluated the effect of peripheral injections of a beta3 adrenergic agonist, BRL-37,344 on food intake and whether this inhibition could be blocked by a nonspecific beta-adrenergic antagonist, propranolol, given peripherally or into the central nervous system. When BRL-37,344
K Koike et al.
European journal of pharmacology, 334(2-3), 217-221 (1997-11-22)
Beta-adrenoceptor-mediated relaxation of guinea pig taenia caecum was investigated by studying the effects of the beta3-adrenoceptor agonists, BRL37344A [(R*,R*)-(+/-)-4-[2'-[2-hydroxy-2-(3-chlorophenyl) ethylamino] propyl] phenoxyacetic acid sodium salt sesquihydrate] and BRL35135A [(R*,R*)-(+/-)-methyl-4-[2-[2-hydroxy-2-(3-chlorophenyl) ethylamine] propyl] phenoxyacetate hydrobromide]. BRL37344A and BRL35135A caused dose-dependent relaxation of
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| B169-5MG | 04061832088815 |
| B169-25MG | 04061833426326 |