conjugate
biotin conjugate
Quality Level
assay
≥97%
form
solid
mol wt
~15000 Da
solubility
H2O: soluble 1 mg/mL, clear, colorless
storage temp.
2-8°C
Application
肝素-生物素用于转染研究，用于开发自组装的三链体，例如聚酰胺基胺树枝状聚合物和DNA（PAMAM/DNA）肝素-生物素三链体，用于靶向基因转运，并改善转染。该三链体可用于固定蛋白质如乳铁蛋白和溶菌酶以及核酸。
Other Notes
猪肠粘膜肝素偶联的生物素
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
Conjugation of polyamidoamine dendrimers on biodegradable microparticles for nonviral gene delivery.
Xue-Qing Zhang et al.
Bioconjugate chemistry, 18(6), 2068-2076 (2007-09-13)
We report on the preparation and characterization of poly(D, L-lactide-co-glycolide) (PLGA) microparticles with surface-conjugated polyamidoamine (PAMAM) dendrimers of varying generations. The buffering capacity and zeta-potential of the PLGA PAMAM microparticles increased with increasing generation level of the PAMAM dendrimer conjugated.
Dzmitry Shcharbin et al.
Journal of controlled release : official journal of the Controlled Release Society, 141(2), 110-127 (2009-10-10)
This paper reviews different techniques for analyzing the transfection efficiencies and cytotoxicities of dendriplexes-complexes of nucleic acids with dendrimers. Analysis shows that three plasmids are mainly used in transfection experiments: plasmid DNA encoding luciferase from the firefly Photinus pyralis, beta-galactosidase
Kelly M Kitchens et al.
Advanced drug delivery reviews, 57(15), 2163-2176 (2005-11-18)
This article summarizes our efforts to evaluate the potential of poly (amidoamine) (PAMAM) dendrimers as carriers for oral drug delivery. Specifically, the permeability of a series of cationic PAMAM-NH2 (G0-G4) dendrimers across Caco-2 cell monolayers was evaluated as a function
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| B9806-10MG | 04061833444009 |