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关于此项目
线性分子式:
C32H46N5O11F
化学文摘社编号:
分子量:
695.73
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
12352209
MDL number:
biological source
synthetic (organic)
Quality Level
assay
≥95%
form
powder
color
white
solubility
DMSO: soluble
shipped in
dry ice
storage temp.
−20°C
SMILES string
COC(=O)C[C@H](NC(=O)[C@H](C)NC(=O)[C@@H](NC(=O)[C@H](CC(=O)OC)NC(=O)[C@@H](NC(=O)OCc1ccccc1)C(C)C)C(C)C)C(=O)CF
InChI
1S/C32H46FN5O11/c1-17(2)26(30(44)34-19(5)28(42)35-21(23(39)15-33)13-24(40)47-6)37-29(43)22(14-25(41)48-7)36-31(45)27(18(3)4)38-32(46)49-16-20-11-9-8-10-12-20/h8-12,17-19,21-22,26-27H,13-16H2,1-7H3,(H,34,44)(H,35,42)(H,36,45)(H,37,43)(H,38,46)/t19-,21-,22-,26-,27-/m0/s1
InChI key
ANTIWMNLIROOQF-IREHUOSBSA-N
Gene Information
human ... CASP2(835)
mouse ... CASP2(12366)
rat ... CASP2(64314)
Biochem/physiol Actions
A cell-permeable inhibitor of caspase-2, which exhibits competitive and irreversible inhibition.
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
法规信息
新产品
此项目有
Wolfgang W Quitschke
PloS one, 7(6), e39568-e39568 (2012-07-07)
Curcumin preparations typically contain a mixture of polyphenols, collectively referred to as curcuminoids. In addition to the primary component curcumin, they also contain smaller amounts of the co-extracted derivatives demethoxycurcumin and bisdemethoxycurcumin. Curcuminoids can be differentially solubilized in serum, which
Aitziber Buqué et al.
Molecular cancer, 11, 25-25 (2012-04-28)
Metastatic melanoma is a lethal skin cancer and its incidence is rising every year. It represents a challenge for oncologist, as the current treatment options are non-curative in the majority of cases; therefore, the effort to find and/or develop novel
L Gorvel et al.
Cell death & disease, 1, e34-e34 (2011-03-03)
Tropheryma whipplei, the etiological agent of Whipple's disease, is an intracellular bacterium that infects macrophages. We previously showed that infection of macrophages results in M2 polarization associated with induction of apoptosis and interleukin (IL)-16 secretion. In patients with Whipple's disease
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| C1605-1MG | 04061826674017 |