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C2020

α-氰基-4-羟基肉桂酸

≥98% (TLC), powder, monocarboxylic acid transport inhibitor

别名:

α-CCA, α-CHCA, α-氰基, 4-HCCA, ACCA

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关于此项目

线性分子式:
HOC6H4CH=C(CN)CO2H
化学文摘社编号:
28166-41-8
分子量:
189.17
NACRES:
NA.77
PubChem Substance ID:
24892459
UNSPSC Code:
12352106
EC Number:
248-879-1
MDL number:
MFCD00004204
Beilstein/REAXYS Number:
3271427
Assay:
≥98% (TLC)
Form:
powder
Quality level:
300
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产品名称

α-氰基-4-羟基肉桂酸, ≥98% (TLC), powder

Quality Level

300

assay

≥98% (TLC)

form

powder

color

yellow

mp

245-250 °C (lit.)

solubility

H2O: slightly soluble, methanol: water: soluble, polar organic solvents: soluble

storage temp.

2-8°C

SMILES string

OC(=O)\C(=C\c1ccc(O)cc1)C#N

InChI

1S/C10H7NO3/c11-6-8(10(13)14)5-7-1-3-9(12)4-2-7/h1-5,12H,(H,13,14)/b8-5+

InChI key

AFVLVVWMAFSXCK-VMPITWQZSA-N

Application

α5-氰基-4-羟基肉桂酸是用于基质辅助激光解吸/电离飞行时间（MALDI-TOF）质谱的一种有用的疏水性基质溶液。将其用作基质溶液，成功地分析了抗生素、肽核酸（一类新的DNA模拟物）和质量高达66,000 Da的蛋白。
α5-氰基-4-羟基肉桂酸已被用于阻断单羧酸盐转运蛋白。

Biochem/physiol Actions

α-氰基-4-羟基肉桂酸可充当一元羧酸转运的特异性抑制剂，包括乳酸和丙酮酸的转运。据报道，其还可阻断β-细胞顶端阴离子交换（IC50 为2.4 mM）。

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pictograms

Exclamation mark
GHS07

signalword

Warning

hcodes

H317

Hazard Classifications

Skin Sens. 1B

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number
MKCN9036
MKCK1270
MKCJ2237
MKCH2027
MKCG5046

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Product Information Sheet - C2020
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J P Barnard et al.
The Journal of biological chemistry, 268(5), 3654-3661 (1993-02-15)
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全球贸易项目编号

货号GTIN
C2020-10G04061833475003
C2020-25G04061833475010