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C3649

CHAPSO

≥98%

别名:

3-[(3-胆胺丙基)二甲基氨基]-2-羟基-1-丙磺酸内盐

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关于此项目

经验公式（希尔记法）:
C32H58N2O8S
化学文摘社编号:
82473-24-3
分子量:
630.88
UNSPSC Code:
12161900
NACRES:
NA.25
PubChem Substance ID:
24892634
MDL number:
MFCD00081079
Beilstein/REAXYS Number:
5842642
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biological source

animal

description

zwitterionic

assay

≥98%

form

powder

mol wt

micellar avg mol wt 7000

aggregation number

11

technique(s)

protein quantification: suitable

impurities

≤5% Water (Karl Fischer)

conductivity

≤100 μmho per cm at 24 °C (0.5 M aqueous solution)

CMC

8 mM (20-25°C)

mp

184-186 °C (lit.)

transition temp

cloud point 90 °C

solubility

water: soluble 10 g/L at 20 °C

SMILES string

[H][C@@]12C[C@H](O)CC[C@]1(C)[C@@]3([H])C[C@H](O)[C@]4(C)[C@]([H])(CC[C@@]4([H])[C@]3([H])[C@H](O)C2)[C@H](C)CCC(=O)NCCC[N+](C)(C)CC(O)CS([O-])(=O)=O

InChI

1S/C32H58N2O8S/c1-20(7-10-29(39)33-13-6-14-34(4,5)18-23(36)19-43(40,41)42)24-8-9-25-30-26(17-28(38)32(24,25)3)31(2)12-11-22(35)15-21(31)16-27(30)37/h20-28,30,35-38H,6-19H2,1-5H3,(H-,33,39,40,41,42)/t20-,21+,22-,23?,24-,25+,26+,27-,28+,30+,31+,32-/m1/s1

InChI key

GUQQBLRVXOUDTN-XOHPMCGNSA-N

General description

CHAPSO 是非变性两性离子胆盐衍生物。 通过添加功能性羟基衍生自 Chaps。

Application

CHAPSO用于：
  • 在一项研究中，评估两种转运蛋白脂质体的溶解和重建过程
  • 在一项研究中，研究新型bicelle体系在宽温度范围内对大分子进行定向
  • 与二月桂酰基磷脂酰胆碱（DLPC）混合，用固态核磁共振（NMR）技术中研究膜相关蛋白
具有类似于 CHAPS 特性的非变性两性离子洗涤剂，然而由于具有更强极性的头部基团而更易溶解。适用于内在膜蛋白的增溶。

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存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number
SLBG1674V
SLBD5164V
116K5304
056K5317
066K5314

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J Cladera et al.
European journal of biochemistry, 243(3), 798-804 (1997-02-01)
The process of liposome solubilization and reconstitution of two transport proteins have been studied using Chaps and Chapso (3-[(3-cholamidopropyl)dimethylammonio]-2- hydroxy-1-propanesulfonate). The solubilization of unilamellar liposomes was followed by absorption experiments and the process was shown to fit well to the
S Cavagnero et al.
Journal of biomolecular NMR, 13(4), 387-391 (1999-06-03)
We have prepared and characterized a novel bicelle system composed of 1,2-di-O-dodecyl-sn-glycero-3-phosphocholine (DIODPC) and 3-(chloramidopropyl)dimethylammonio-2-hydroxyl-1-propane sulfonate (CHAPSO). At the optimal DIODPC/CHAPSO molar ratio of 4.3:1, this medium becomes magnetically oriented from pH 6.5 down to pH 1.0. Unlike previously reported
Magnetically orientable phospholipid bilayers containing small amounts of a bile salt analogue, CHAPSO.
Sanders CR and Prestegard J
Biophysical Journal, 58(2), 447-460 (1990)
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全球贸易项目编号

货号GTIN
C3649-1G04061833486139
C3649-25G04061833618677
C3649-500MG04061833486146
C3649-5G04061833610091