C3930
钙调蛋白抑制剂
solid
别名:
1- [双（4-氯苯基）甲基]-3- [2,4-二氯-β-氯化咪唑, 1- [双（4-氯苯基）甲基]-3- [2-（2,4-二氯苯基）-2-（2,4-二氯苄氧基）乙基]-1H-咪唑氯化物, R 24571
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关于此项目
经验公式（希尔记法）:
C31H23Cl7N2O
化学文摘社编号:
分子量:
687.70
UNSPSC Code:
12352202
NACRES:
NA.77
PubChem Substance ID:
MDL number:
Beilstein/REAXYS Number:
6470244
Form:
solid
Quality level:
form
solid
Quality Level
color
white
storage temp.
2-8°C
SMILES string
[Cl-].Clc1ccc(cc1)C(c2ccc(Cl)cc2)[n+]3ccn(CC(OCc4ccc(Cl)cc4Cl)c5ccc(Cl)cc5Cl)c3
InChI
1S/C31H23Cl6N2O.ClH/c32-23-6-1-20(2-7-23)31(21-3-8-24(33)9-4-21)39-14-13-38(19-39)17-30(27-12-11-26(35)16-29(27)37)40-18-22-5-10-25(34)15-28(22)36;/h1-16,19,30-31H,17-18H2;1H/q+1;/p-1
InChI key
YGEIMSMISRCBFF-UHFFFAOYSA-M
Biochem/physiol Actions
钙调素调节酶抑制剂。它也被认为可以直接阻断平滑肌细胞的钙通道。
Preparation Note
可用 DMSO 制备 5 mM 储备液，然后用缓冲液稀释至 0.01 mM。DMSO 溶液可储存数周。
Disclaimer
在水溶液中与玻璃表面结合。
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存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
Mohamad Sabbah et al.
Bioorganic & medicinal chemistry, 19(16), 4868-4875 (2011-07-26)
Thirty N,N'-disubstituted imidazolium salts have been synthesized and evaluated as LuxR antagonists. Substitution on one of the imidazolium nitrogen atoms includes benzhydryl, fluorenyl or cyclopentyl substituent, and alkyl chains of various lengths on the second one. Most of these compounds
Shi-Hong Gu et al.
Journal of insect physiology, 56(1), 93-101 (2009-10-06)
Our previous studies showed that the prothoracicotropic hormone (PTTH) stimulated extracellular signal-regulated kinase (ERK) phosphorylation in prothoracic glands of Bombyx mori both in vitro and in vivo. In the present study, the signaling pathway by which PTTH activates ERK phosphorylation
Qi Xi et al.
American journal of physiology. Heart and circulatory physiology, 301(2), H428-H433 (2011-05-17)
Glutamate-stimulated, astrocyte-derived carbon monoxide (CO) causes cerebral arteriole dilation by activating smooth muscle cell large-conductance Ca(2+)-activated K(+) channels. Here, we examined the hypothesis that glutamate activates heme oxygenase (HO)-2 and CO production via the intracellular Ca(2+) concentration ([Ca(2+)](i))/Ca(2+)-calmodulin signaling pathway
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| C3930-10MG | 04061833023907 |
| C3930-25MG | 04061833023914 |
| C3930-5MG | 04061833486603 |