C4042
卡托普利
≥98% (HPLC), powder, angiotensin converting enzyme inhibitor
别名:
N-[(S)-3-巯基-2-甲基丙酰基]-L-脯氨酸
选择尺寸
关于此项目
产品名称
卡托普利, ≥98% (HPLC), powder
biological source
synthetic
Quality Level
assay
≥98% (HPLC)
form
powder
color
white to off-white
mp
104-108 °C (lit.)
solubility
water: 100 mg/mL, clear to very slightly hazy, colorless to faintly yellow
originator
Bristol-Myers Squibb
storage temp.
room temp
SMILES string
C[C@H](CS)C(=O)N1CCC[C@H]1C(O)=O
InChI
1S/C9H15NO3S/c1-6(5-14)8(11)10-4-2-3-7(10)9(12)13/h6-7,14H,2-5H2,1H3,(H,12,13)/t6-,7+/m1/s1
InChI key
FAKRSMQSSFJEIM-RQJHMYQMSA-N
Gene Information
human ... ACE(1636), AGTR1(185), AGTR2(186), ECE1(1889)
rat ... Ace(24310)
Application
- 用于检查卡托普利治疗时机对横向主动脉缩窄（TAC）小鼠疗效的影响
- 用作血管紧张素转化酶抑制剂，口服送药给自由活动且正常血压的京都大鼠，以研究其血管生成抑制作用以及与其他药物的相互依赖性
- 用作分光光度测定中的阳性对照，以研究血管紧张素转化酶抑制活性
Biochem/physiol Actions
Features and Benefits
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signalword
Danger
hcodes
Hazard Classifications
Muta. 2 - Repr. 1B
存储类别
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
wgk
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges
商品
Discover critical characteristics to consider when working with enzyme inhibitors, such as cell permeability, the prozone effect, and Lipinski’s rule of 5.
Discover Bioactive Small Molecules for ADME/Tox
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| C4042-25G | 04061833487495 |
| C4042-5G | 04061833487518 |