C4522
西咪替丁
histamine H2 receptor antagonist, powder
别名:
SKF-92334
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关于此项目
经验公式（希尔记法）:
C10H16N6S
化学文摘社编号:
分子量:
252.34
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
12352200
EC Number:
257-232-2
MDL number:
Form:
powder
Quality level:
产品名称
西咪替丁,
form
powder
Quality Level
originator
GlaxoSmithKline
storage temp.
2-8°C
SMILES string
CN\C(NC#N)=N\CCSCc1nc[nH]c1C
InChI
1S/C10H16N6S/c1-8-9(16-7-15-8)5-17-4-3-13-10(12-2)14-6-11/h7H,3-5H2,1-2H3,(H,15,16)(H2,12,13,14)
InChI key
AQIXAKUUQRKLND-UHFFFAOYSA-N
Gene Information
human ... ABCB1(5243), CYP1A2(1544), CYP3A4(1576), HRH2(3274), SLC9A2(6549), SLC9A5(6553)
mouse ... Abcb1a(18671), Abcb1b(18669)
rat ... Slc9a1(24782), Slc9a3(24784), Slc9a5(192215)
Biochem/physiol Actions
H2组胺受体拮抗剂；I1咪唑啉受体激动剂；抗溃疡剂。通过抑制内皮细胞表面上E-选择蛋白的表达来阻断癌症转移，从而阻断肿瘤细胞的粘附。
Features and Benefits
该化合物由 GlaxoSmithKline 开发。想要浏览其他由制药公司开发的化合物以及已批准药物/候选药物清单，请单击此处。
这种化合物是 ADME 毒性研究的特色产品。点击此处发现更多特色 ADME 毒性产品。在sigma.com/discover-bsm可了解更多关于生物活性小分子的其他研究领域。
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存储类别
11 - Combustible Solids
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全球贸易项目编号
| 货号 | GTIN |
|---|---|
| C4522-25G | 04061832089812 |
| C4522-10G | 04061833492291 |
| C4522-5G | 04061833492307 |