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Merck
CN

C4710

单克隆抗-细胞周期蛋白A 小鼠抗

clone CY-A1, ascites fluid

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关于此项目

UNSPSC Code:
12352203
NACRES:
NA.41
MDL number:
Conjugate:
unconjugated
Clone:
CY-A1, monoclonal
Application:
ARR, ICC, WB
Citations:
41
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biological source

mouse

Quality Level

conjugate

unconjugated

antibody form

ascites fluid

antibody product type

primary antibodies

clone

CY-A1, monoclonal

mol wt

antigen 60 kDa

contains

15 mM sodium azide

species reactivity

mouse, human, monkey, bovine

technique(s)

immunocytochemistry: suitable, microarray: suitable, western blot: 1:1,000 using a mouse NIH 3T3 cell extract

isotype

IgG2a

UniProt accession no.

shipped in

dry ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... CCNA2(890)
mouse ... Ccna2(12428)

General description

细胞周期蛋白 A 是 S 期的核蛋白,它与 cdk2 和 cdc2 结合。与细胞周期蛋白 A 特异性反应的单克隆抗体的可用性使得细胞周期蛋白 A 的亚细胞检测和定位,以及细胞周期蛋白水平的相对差异(作为细胞周期阶段的功能)的测量成为可能。

Immunogen

重组牛细胞周期蛋白 A。

Application

小鼠单克隆抗 Cyclin A 抗体适用于:
  • 免疫细胞化学
  • 微阵列
  • 蛋白质印迹(使用小鼠 NIH 3T3 细胞提取物,1:1,000 稀释)

Biochem/physiol Actions

该抗体识别牛细胞周期蛋白 A 氨基酸 162-433 中存在的表位。未发现与其他细胞周期蛋白(细胞周期蛋白 B、D 或 E)有交叉反应。

Disclaimer

除非我们的产品目录或产品附带的其他公司文档另有说明,否则我们的产品仅供研究使用,不得用于任何其他目的,包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或任何类型的消费或应用于人类或动物。


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存储类别

10 - Combustible liquids

wgk

nwg

flash_point_f

Not applicable

flash_point_c

Not applicable

法规信息

常规特殊物品
动物来源生物产品

此项目有



历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Matthew Hoare et al.
Nature cell biology, 18(9), 979-992 (2016-08-16)
Senescence, a persistent form of cell-cycle arrest, is often associated with a diverse secretome, which provides complex functionality for senescent cells within the tissue microenvironment. We show that oncogene-induced senescence is accompanied by a dynamic fluctuation of NOTCH1 activity, which
Chiung-Yueh Hsu et al.
Journal of virology, 81(1), 384-394 (2006-10-13)
The papillomavirus E1 protein is essential for the initiation of viral replication. We previously showed that the bovine papillomavirus E1 protein is unstable and becomes resistant to ubiquitin-mediated degradation when tightly bound to cyclin E-cyclin-dependent kinase 2 (Cdk2) before the
Jason M Bodily et al.
Journal of virology, 85(17), 8852-8862 (2011-06-24)
Human papillomaviruses (HPVs) are the causative agents of several important genital and other mucosal cancers. The HPV16 E7 gene encodes a viral oncogene that is necessary for the continued growth of cancer cells, but its role in the normal, differentiation-dependent



全球贸易项目编号

货号GTIN
C4710-.2ML04061837867774