C5135
蓖麻油，乙氧基化
pH range 6.0-8.0
别名:
Cremophor® EL, PEG-35蓖麻油, 乙氧基化蓖麻油, 聚甲醛-35蓖麻油
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关于此项目
description
non-ionic
Quality Level
form
liquid
mol wt
~2500 g/mol
pH range
6.0-8.0
HLB
12 - 14
application(s)
sample preservation
SMILES string
ClCC(OC(=O)N)CCl
InChI
1S/C4H7Cl2NO2/c5-1-3(2-6)9-4(7)8/h3H,1-2H2,(H2,7,8)
InChI key
JMNCUXPHXKHBPY-UHFFFAOYSA-N
General description
乙氧基化蓖麻 油是聚环氧乙烷表面活性剂，具有粘性。它的亲水疏水平衡值为12-14。
乙氧基化蓖麻 油是一种非离子增溶剂和乳化剂，是环氧乙烷和蓖麻油反应生成的。它是一种浅黄色油状液体，在26°C以上澄清，气味不强但很特别。
Application
乙氧基化蓖麻 油可用作洗涤剂，增强颜料溶解度和跨膜渗透性。它可用作细胞内药物/激活剂递送的载体。
Biochem/physiol Actions
乙氧基化蓖麻油用于脂质制剂药物和化妆品增溶。乙氧基化蓖麻油适合生产含有水不溶性活性物质等疏水化合物的半固体和液体制剂。由于具有乳化作用，它可用于基于生物膜的药物转运研究。
Other Notes
是蓖麻油和环氧乙烷的一种衍生物。
Legal Information
Cremophor is a registered trademark of BASF SE
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存储类别
10 - Combustible liquids
flash_point_f
494.6 °F - Not applicable
flash_point_c
257 °C - Not applicable
ppe
Eyeshields, Gloves
Independent evaluation of the anatomical and behavioral effects of Taxol in rat models of spinal cord injury.
Popovich PG
Experimental Neurology, 261, 97-97 (2014)
Colloidal nanocarriers for the enhanced cutaneous delivery of naftifine: characterization studies and in vitro and in vivo evaluations
Erdal MS, et al.
International journal of nanomedicine, 11, 1027-1027 (2016)
A nonionic polyethylene oxide (PEO) surfactant model: experimental and molecular dynamics studies of Kolliphor EL
Suys EJA, et al.
Journal of Pharmaceutical Sciences, 108(1), 193-204 (2019)
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| C5135-1KG | 04061833501788 |
| C5135-500G | 04061833501795 |