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C5865

CD437

≥98% (HPLC), retinoic acid receptor (RAR)γ-selective agonist, solid

别名:

6- [3-（1-金刚烷基）-4-羟苯基] -2-萘甲酸, AHPN

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关于此项目

经验公式（希尔记法）:
C27H26O3
化学文摘社编号:
125316-60-1
分子量:
398.49
UNSPSC Code:
12352200
PubChem Substance ID:
24724445
NACRES:
NA.77
MDL number:
MFCD03106506
Assay:
≥98% (HPLC)
Form:
solid
Quality level:
100
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产品名称

CD437, ≥98% (HPLC), solid

Quality Level

100

assay

≥98% (HPLC)

form

solid

impurities

~0.5 mol/mol water

color

yellow

mp

271.6-276 °C

solubility

DMSO: >10 mg/mL, H2O: insoluble

storage temp.

−20°C

SMILES string

OC(=O)c1ccc2cc(ccc2c1)-c3ccc(O)c(c3)C45CC6CC(CC(C6)C4)C5

InChI

1S/C27H26O3/c28-25-6-5-22(20-1-2-21-11-23(26(29)30)4-3-19(21)10-20)12-24(25)27-13-16-7-17(14-27)9-18(8-16)15-27/h1-6,10-12,16-18,28H,7-9,13-15H2,(H,29,30)

InChI key

LDGIHZJOIQSHPB-UHFFFAOYSA-N

Gene Information

human ... RARA(5914), RARB(5915), RARG(5916)

Biochem/physiol Actions

CD437 是视黄酸受体（RAR）γ-选择性激动剂，γ-选择性视黄酸；凋亡的有效诱导剂。

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number
022M4623V
068K46292
068K46291
068K4629
057K4610

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Fang Tan et al.
Frontiers in microbiology, 10, 2301-2301 (2019-10-28)
Enterococcus faecalis (E. faecalis), a biofilm-forming pathogen, causes nosocomial infections. In recent years, drug resistance by enterococci has become increasingly severe due to widespread antibiotic abuse. Therefore, novel antibacterial agents are urgently needed. In this study, the synthetic retinoid compound
Hideyuki Shirasawa et al.
The American journal of sports medicine, 49(2), 332-339 (2021-01-12)
The infiltration of fat tissue into skeletal muscle, a condition referred to as muscle fatty infiltration or fatty degeneration, is regarded as an irreversible event that significantly compromises the motor function of skeletal muscle. To investigate the effect of retinoic
Almudena Bosch et al.
Breast cancer research : BCR, 14(4), R121-R121 (2012-08-28)
Retinoic acid signaling plays key roles in embryonic development and in maintaining the differentiated status of adult tissues. Recently, the nuclear retinoic acid receptor (RAR) isotypes α, β and γ were found to play specific functions in the expansion and
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全球贸易项目编号

货号GTIN
C5865-25MG04061832954189
C5865-5MG04061832954196