C7397
环磷酰胺 一水合物
ISOPAC®
别名:
2-[双(2-氯乙基)氨基]四氢-2H-1,3,2-噁磷-2-氧化物, Cytoxan
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关于此项目
经验公式（希尔记法）:
C7H15Cl2N2O2P · H2O
化学文摘社编号:
分子量:
279.10
UNSPSC Code:
51112507
NACRES:
NA.25
PubChem Substance ID:
EC Number:
200-015-4
Beilstein/REAXYS Number:
4678992
MDL number:
Quality Level
assay
97.0-103.0% (HPLC)
form
powder
mp
49-51 °C (lit.)
storage temp.
2-8°C
SMILES string
[H]O[H].ClCCN(CCCl)P1(=O)NCCCO1
InChI
1S/C7H15Cl2N2O2P.H2O/c8-2-5-11(6-3-9)14(12)10-4-1-7-13-14;/h1-7H2,(H,10,12);1H2
InChI key
PWOQRKCAHTVFLB-UHFFFAOYSA-N
Application
环磷酰胺是氮芥类烷化剂，被广泛用于抗肿瘤和抗免疫药物的作用机理研究。
Biochem/physiol Actions
广泛用于癌症化疗的细胞毒性氮芥衍生物。它可与 DNA 交联、导致链断裂并诱导突变。
环磷酰胺是一种广泛用于癌症化疗的具有细胞毒性的氮芥衍生物。它可与 DNA 交联、导致链断裂并诱导突变。其临床活性与乙醛脱氢酶 1 (ALDH1) 的活性降低相关。
Packaging
包装在 100 mL 血清瓶中，具有硅/PTFE 隔膜和铝封。
Preparation Note
将内容物溶于 100 mL 溶剂中，得到 1% 溶液。
Legal Information
Isopac is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
将相容溶剂直接注入小瓶中，可制备任何所需规格的溶液，无需暴露。
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signalword
Danger
hcodes
Hazard Classifications
Acute Tox. 3 Oral - Carc. 1B - Muta. 1B - Repr. 1A
存储类别
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
wgk
WGK 3
ppe
Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges
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全球贸易项目编号
| 货号 | GTIN |
|---|---|
| C7397-1G | 04061833512326 |