biological source
synthetic (organic)
assay
≥98% (HPLC; detection at 205 nm)
form
powder
mp
44-47 °C (lit.)
functional group
ester
shipped in
ambient
storage temp.
−20°C
SMILES string
[H]\C(CCCCCCCC)=C(/[H])CCCCCCCC(=O)O[C@H]1CC[C@@]2(C)C(C1)=CC[C@]3([H])[C@]2([H])CC[C@]4(C)[C@]([H])(CC[C@@]34[H])[C@H](C)CCCC(C)C
InChI
1S/C45H78O2/c1-7-8-9-10-11-12-13-14-15-16-17-18-19-20-21-25-43(46)47-38-30-32-44(5)37(34-38)26-27-39-41-29-28-40(36(4)24-22-23-35(2)3)45(41,6)33-31-42(39)44/h14-15,26,35-36,38-42H,7-13,16-25,27-34H2,1-6H3/b15-14-/t36-,38+,39+,40-,41+,42+,44+,45-/m1/s1
InChI key
RJECHNNFRHZQKU-RMUVNZEASA-N
Application
采用油酸胆甾醇酯研究硅水凝胶联系镜吸收泪脂、 胆固醇和胆固醇酯的能力。它也被用于开发电流型胆固醇生物传感器。
Biochem/physiol Actions
血浆中的胆固醇以酯化形式存在，如胆固醇油酸酯。肝脏是胆固醇酯的主要来源，胆固醇酯在释放到血浆中时可富集 LDL 颗粒。富含油酸胆固醇酯的脂蛋白的分泌与冠状动脉粥样硬化的发病机制密切相关。
Preparation Note
油酸胆甾醇酯在氯仿中生成澄清无色溶液，浓度为 100 mg/mL。
存储类别
11 - Combustible Solids
wgk
WGK 3
ppe
Eyeshields, Gloves, type N95 (US)
商品
胆固醇酯化可改善运输。胆固醇酯可更轻松地封装在脂蛋白内部-增加了在血液中可轻松运输的胆固醇数量。
Cholesterol esterification enhances transport efficiency in lipoproteins for increased blood stream transport.
Marta Overchuk et al.
ACS nano, 13(4), 4560-4571 (2019-03-28)
Lipoprotein mimetic nanostructures, which consist of an amphiphilic lipid shell, a hydrophobic core, and an apolipoprotein mimetic peptide, serve as a versatile platform for the design of drug delivery vehicles as well as the investigation of supramolecular assemblies. Porphyrin incorporation
Design of an Interference-Free Cholesterol Amperometric Biosensor Based on the Electrosynthesis of Polymeric Films of Diaminonaphthalene Isomers
Garcia-Ruiz E et al
Electroanalysis, 16, 497-504 (2004)
L L Rudel et al.
The Journal of clinical investigation, 100(1), 74-83 (1997-07-01)
Relationships among plasma lipoprotein cholesterol, cholesterol secretion by the isolated, perfused liver, and coronary artery atherosclerosis were examined in African green monkeys fed diets containing cholesterol and 35% of calories as fat enriched in polyunsaturated, monounsaturated, or saturated fatty acids.
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| C9253-100MG | 04061833530375 |
| C9253-500MG | 04061833530405 |
| C9253-1G | 04061833530382 |
| C9253-250MG | 04061833530399 |