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C9538

辅酶 Q10

≥98% (HPLC), powder, antioxidant

别名:

CoQ10, Q-10, 辅酶Q10, 辅酶Q50

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关于此项目

经验公式（希尔记法）:
C59H90O4
化学文摘社编号:
303-98-0
分子量:
863.34
NACRES:
NA.77
PubChem Substance ID:
24893170
UNSPSC Code:
12352200
EC Number:
206-147-9
MDL number:
MFCD00042919
Beilstein/REAXYS Number:
1900141
Assay:
≥98% (HPLC)
Form:
powder
Quality level:
200
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产品名称

辅酶 Q10, ≥98% (HPLC)

Quality Level

200

assay

≥98% (HPLC)

form

powder

color

yellow to dark orange

mp

49 °C

application(s)

cell analysis

storage temp.

−20°C

SMILES string

O=C(C(OC)=C1OC)C(C/C=C(C)/CC/C=C(CC/C=C(CC/C=C(CC/C=C(CC/C=C(CC/C=C(C)/CC/C=C(C)/CC/C=C(C)/CCC=C(C)C)\C)\C)\C)\C)\C)=C(C)C1=O

InChI

1S/C59H90O4/c1-44(2)24-15-25-45(3)26-16-27-46(4)28-17-29-47(5)30-18-31-48(6)32-19-33-49(7)34-20-35-50(8)36-21-37-51(9)38-22-39-52(10)40-23-41-53(11)42-43-55-54(12)56(60)58(62-13)59(63-14)57(55)61/h24,26,28,30,32,34,36,38,40,42H,15-23,25,27,29,31,33,35,37,39,41,43H2,1-14H3/b45-26+,46-28+,47-30+,48-32+,49-34+,50-36+,51-38+,52-40+,53-42+

InChI key

ACTIUHUUMQJHFO-UPTCCGCDSA-N

General description

辅酶 Q（CoQ）又称泛醌，是一种脂溶性抗氧化剂，是线粒体电子传递链的重要组成部分。该分子含有一个生物活性醌，包含一个苯醌环和一个异戊二烯侧链。Q10在细胞质和线粒体中合成（），通过有氧细胞呼吸产生ATP。免疫系统的顺利运行和心血管健康都需要CoQ10（）。抑制炎症基因表达的能力显示了它的抗炎特性（）。 基因缺陷或衰老导致CoQ10缺乏，表现为免疫功能受到抑制。()

Application

辅酶Q10（CoQ10）已被用于：
  • 作为一种生物活性化合物，在体外研究其免疫调节特性
  • 高效液相色谱的标准品
  • 研究其对运动大鼠主动脉的影响
  • 细胞CoQ摄取检测

Biochem/physiol Actions

辅酶Q10是一种内源性细胞抗氧化剂，是电子传递链的重要组成部分。辅酶Q10参与有氧细胞呼吸和ATP形式的能量产生。

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存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number
SLCL3912
SLCK0119
SLCF9505
SLCB9480
SLBX4909

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商品

膳食抗氧化剂

抗氧化剂可保护生物系统免受含氧自由基和氧化还原过渡金属离子（如铁、铜和镉）引起的氧化损伤。

Dietary Antioxidants

Antioxidants protect biological systems from oxidative damage produced by oxygen-containing free radicals and from redoxactive transition metal ions such as iron, copper, and cadmium.

Discover Bioactive Small Molecules for Lipid Signaling Research

Discover Bioactive Small Molecules for Lipid Signaling Research

Courtney M Anderson et al.
Cell reports, 10(4), 505-515 (2015-01-27)
Brown adipose tissue (BAT) possesses the inherent ability to dissipate metabolic energy as heat through uncoupled mitochondrial respiration. An essential component of the mitochondrial electron transport chain is coenzyme Q (CoQ). While cells synthesize CoQ mostly endogenously, exogenous supplementation with
E L Appelkvist et al.
The Clinical investigator, 71(8 Suppl), S97-102 (1993-01-01)
Inhibitors of hydroxymethylglutaryl coenzyme A reductase are used clinically to decrease blood levels of low-density lipoprotein cholesterol in hypercholesterolemic patients. However, little is known about the possible effects of these inhibitors on dolichol and cholesterol synthesis. Oral administration of mevinolin
N Okudan et al.
Acta physiologica Hungarica, 99(1), 40-50 (2012-03-20)
In this study, the effect of long-term supplementation of coenzyme Q10 (CoQ10) on the responses of swim-trained rat aorta was investigated. Twenty-four adult male Wistar rats were divided into four groups: untrained, trained, untrained+CoQ10, and trained+CoQ10 group. In the trained
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全球贸易项目编号

货号GTIN
C9538-100MG04061833530818
C9538-1G04061833530825
C9538-500MG04061833530832