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Merck
CN

CS0410

谷胱甘肽S-转移酶(GST)活性检测试剂盒

sufficient for 500 multiwell tests

别名:

GST 酶活性测定试剂盒

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关于此项目

UNSPSC Code:
12161503
EC Number:
202-551-4
NACRES:
NA.84
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usage

sufficient for 500 multiwell tests

Quality Level

shipped in

dry ice

storage temp.

−20°C

Gene Information

General description

谷胱甘肽S-转移酶 (GST) 检测试剂盒用于测定总GST的活性。适用于细胞和细菌裂解物、组织匀浆以及血浆
和红细胞裂解物样品。

Application

该谷胱甘肽S-转移酶检测试剂盒采用1-氯-2,4-二硝基苯(CDNB),适用于广泛的GST同工酶。基本原理是谷胱甘肽硫醇基团结合到CDNB底物上后,在340nm处的吸光度会增加。

Biochem/physiol Actions

谷胱甘肽S-转移酶 (GST)是在哺乳动物解除许多外源物毒素过程中发挥重要作用的一组酶。该酶可将谷胱甘肽的硫醇基团连接到亲电的外源物上,保护细胞免受毒物损害,进一步帮助细胞抵抗化合物诱变、致癌和毒性作用。GST活性广泛存在于植物、昆虫、酵母、细菌以及大多数哺乳动物组织中,尤其是在解毒过程中发挥关键作用的肝脏中。


仅试剂盒组分

产品编号
说明

  • Dulbecco's Phosphate Buffered Saline 100 mL

  • L-Glutathione Reduced 1 g

  • GST (Control) .1 mL

  • Sample Buffer 5 mL

  • Substrate (CDNB) 1.2 mL

signalword

Danger

flash_point_f

Not applicable

flash_point_c

Not applicable

Hazard Classifications

Aquatic Acute 1 - Aquatic Chronic 2 - Eye Irrit. 2 - Flam. Liq. 2 - Skin Sens. 1

存储类别

3 - Flammable liquids

法规信息

低风险生物材料
危险化学品
常规特殊物品

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历史批次信息供参考:

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Maria Sehlstedt et al.
Particle and fibre toxicology, 7, 21-21 (2010-08-24)
Biomass combustion contributes to the production of ambient particulate matter (PM) in rural environments as well as urban settings, but relatively little is known about the health effects of these emissions. The aim of this study was therefore to characterize
Didier Techer et al.
Environmental toxicology, 32(1), 227-240 (2015-12-18)
Gallic and pelargonic acids are biologically derived substances receiving a growing interest as eco-friendly biocides with potential applications in freshwater system management. However, some data gaps remain to address their chronic ecotoxicity issue, particularly for fish. This work aimed at
T Lin et al.
Toxicology, 235(1-2), 1-10 (2007-04-10)
Glutathione (GSH) is one of the most important antioxidants in mammalian cells. It also plays an important role in chemical detoxification. Some evidence showed that polycyclic aromatic hydrocarbons, such as benzo[a]pyrene (B[a]P [50-32-8]), could increase GSH content as a defense



全球贸易项目编号

货号GTIN
CS0410-1KT04061833553107