D0390
NG,NG ′-二甲基-L-精氨酸 二(对羟基偶氮苯对磺酸) 盐
≥99% (TLC)
别名:
SDMA
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关于此项目
经验公式（希尔记法）:
C8H18N4O2 · 2C12H10N2O4S
化学文摘社编号:
分子量:
758.82
MDL number:
UNSPSC Code:
12352202
PubChem Substance ID:
NACRES:
NA.77
biological source
synthetic (organic)
Quality Level
assay
≥99% (TLC)
form
powder
solubility
methanol: 10 mg/mL
storage temp.
room temp
SMILES string
CN\C(NC)=N\CCC[C@H](N)C(O)=O.Oc1ccc(cc1)\N=N\c2ccc(cc2)S(O)(=O)=O.Oc3ccc(cc3)\N=N\c4ccc(cc4)S(O)(=O)=O
InChI
1S/2C12H10N2O4S.C8H18N4O2/c2*15-11-5-1-9(2-6-11)13-14-10-3-7-12(8-4-10)19(16,17)18;1-10-8(11-2)12-5-3-4-6(9)7(13)14/h2*1-8,15H,(H,16,17,18);6H,3-5,9H2,1-2H3,(H,13,14)(H2,10,11,12)/b2*14-13+;/t;;6-/m..0/s1
InChI key
HISUXCNNXYEHER-YJSASASGSA-N
Application
血浆 对称-二甲基精氨酸一直被认为是肝、肾功能障碍的标志。开发了用于鉴别血浆和尿液样品中精氨酸和 非对称-和 对称-二甲基精氨酸的灵敏 LC-MS 方法。
血浆 对称-二甲基精氨酸一直被认为是肝、肾功能障碍的标志。开发了用于鉴别血浆和尿液样品中精氨酸和非对称和 对称二甲基精氨酸的灵敏 LC-MS 方法。
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
Eva Buresova et al.
Journal of veterinary internal medicine, 33(2), 516-522 (2019-01-12)
Measurement of serum creatinine (sCr) and urea nitrogen fail to detect decreased renal function in many hyperthyroid cats because of low muscle mass and glomerular hyperfiltration of affected cats. Serum symmetric dimethylarginine (sSDMA) is an earlier and more sensitive renal
Elevation of serum asymmetrical and symmetrical dimethylarginine in patients with advanced glaucoma.
Shahrbanou Javadiyan et al.
Investigative ophthalmology & visual science, 53(4), 1923-1927 (2012-03-08)
Asymmetric dimethylarginine (ADMA) and symmetric dimethylarginine (SDMA) are the dimethylated isomeric derivatives of the amino acid L-arginine. ADMA is an endogenous inhibitor of nitric oxide synthase (NOS), while SDMA is a competitive inhibitor of cellular uptake of L-arginine, the substrate
Olga Kruszelnicka et al.
Amino acids, 47(9), 1951-1959 (2015-04-11)
Metformin, the drug of first choice in type 2 diabetes mellitus (T2DM), reduces cardiovascular (CV) morbidity and mortality in part independently of improved glycemic control and changes in traditional risk factors. However, there are discordant reports on the effects of
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| D0390-5MG | 04061833557648 |
| D0390-25MG | 04061832947099 |