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Merck
CN

D6128

αβ二氢胆固醇

≥95%

别名:

β-胆甾醇, 3β-羟基-5α-胆甾烷, 二氢胆甾醇

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关于此项目

经验公式(希尔记法):
C27H48O
化学文摘社编号:
分子量:
388.67
UNSPSC Code:
12352211
NACRES:
NA.28
PubChem Substance ID:
EC Number:
201-315-8
Beilstein/REAXYS Number:
2418594
MDL number:
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biological source

synthetic (organic)

Quality Level

assay

≥95%

form

powder

shipped in

ambient

storage temp.

room temp

SMILES string

CC(C)CCC[C@@H](C)[C@H]1CC[C@H]2[C@@H]3CC[C@H]4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C

InChI

1S/C27H48O/c1-18(2)7-6-8-19(3)23-11-12-24-22-10-9-20-17-21(28)13-15-26(20,4)25(22)14-16-27(23,24)5/h18-25,28H,6-17H2,1-5H3/t19-,20+,21+,22+,23-,24+,25+,26+,27-/m1/s1

InChI key

QYIXCDOBOSTCEI-QCYZZNICSA-N

Gene Information

human ... POLA1(5422), TOP2A(7153)
rat ... Polb(29240)

Application

使用 HPLC,将 5α-胆甾烷-3β-醇用作脂质分析的标准。

Biochem/physiol Actions

5α-胆甾烷-3β-醇通过肠道微生物的作用来源于胆固醇。已知在存在钠离子的情况下可诱导兔胆石形成。


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存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)



历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Anna Bertolini et al.
American journal of physiology. Gastrointestinal and liver physiology, 316(3), G404-G411 (2019-01-18)
The gastrointestinal phenotype of cystic fibrosis (CF) features intestinal bile acid (BA) malabsorption, impaired intestinal farnesoid X receptor (FXR) activation, and consequently reduced fibroblast growth factor 19 (FGF19, FGF15 in mice) production. The osmotic laxative polyethylene glycol (PEG) has been
Benjamin L Stottrup et al.
Biophysical journal, 90(9), 3176-3183 (2006-02-08)
We investigate the miscibility phase behavior of lipid monolayers containing a wide variety of sterols. Six of the sterols satisfy a definition from an earlier study of "membrane-active sterols" in bilayers (cholesterol, epicholesterol, lathosterol, dihydrocholesterol, ergosterol, and desmosterol), and six
IDENTIFICATION OF ALLODEOXYCHOLIC ACID AS THE MAJOR COMPONENT OF GALLSTONES INDUCED IN THE RABBIT BY 5-ALPHA-CHOLESTAN-3-BETA-OL.
A F HOFMANN et al.
The Journal of biological chemistry, 239, 2813-2821 (1964-09-01)



全球贸易项目编号

货号GTIN
D6128-10G04061833587256
D6128-25G04061833587263