主要文件

查看所有文档

D7408

2′,5′-Dideoxyadenosine

Name: 2&#8242;,5&#8242;-Dideoxyadenosine
Brand: SIGMA

≥95% (HPLC), Adenylyl cyclase inhibitor, solid

别名:

2ʹ,5ʹ-dd-Ado, NSC 95943

登录查看组织和合同定价。

选择尺寸

变更视图

关于此项目

经验公式（希尔记法）:

C₁₀H₁₃N₅O₂

化学文摘社编号:

6698-26-6

分子量:

235.24

UNSPSC Code:

41106305

PubChem Substance ID:

24894132

NACRES:

NA.77

MDL number:

MFCD00210904

Assay:

≥95% (HPLC)

Form:

solid

Quality level:

100

技术服务

需要帮助？我们经验丰富的科学家团队随时乐意为您服务。

让我们为您提供帮助

属性

产品名称

2′,5′-Dideoxyadenosine, ≥95% (HPLC), solid

Quality Level

100

assay

≥95% (HPLC)

form

solid

color

white

solubility

DMSO: soluble

storage temp.

−20°C

SMILES string

C[C@H]1O[C@H](C[C@@H]1O)n2cnc3c(N)ncnc23

InChI

1S/C10H13N5O2/c1-5-6(16)2-7(17-5)15-4-14-8-9(11)12-3-13-10(8)15/h3-7,16H,2H2,1H3,(H2,11,12,13)/t5-,6+,7-/m1/s1

InChI key

FFHPXOJTVQDVMO-DSYKOEDSSA-N

Gene Information

rat ... Adcy2(81636)

说明

Application

2′,5′-Dideoxyadenosine has been used to elucidate the mechanism of diligustilide (DLG). It has also been used to inhibit adenylate cyclase (AC).

Biochem/physiol Actions

Cell-permeable adenylyl cyclase inhibitor. IC₅₀ = 2.7 μM in detergent-dispersed rat brain preparations.

Features and Benefits

This compound is a featured product for Cyclic Nucleotide research. Click here to discover more featured Cyclic Nucleotide products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.

This compound is featured on the Adenylyl cyclases page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

Preparation Note

Store at −20 °C after reconstitution.

Still not finding the right product?

Explore all of our products under

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

没有发现合适的版本？

如果您需要特殊版本，可通过批号或批次号查找具体证书。

搜索COA

已有该产品？

在文件库中查找您最近购买产品的文档。

访问文档库

商品

Discover Bioactive Molecules for Nucleotides

Cyclic nucleotides like cAMP modulate cell function via PKA activation and ion channels.

Impaired complement-mediated phagocytosis by HIV type-1-infected human monocyte-derived macrophages involves a cAMP-dependent mechanism.

Rula Azzam et al.

AIDS research and human retroviruses, 22(7), 619-629 (2006-07-13)

HIV-1 infection of cells of macrophage lineage impairs a number of effector functions performed by these cells, including phagocytosis of opsonized pathogens. In this study we investigate the effects of HIV-1 on the mechanism of complement (C')-mediated phagocytosis by human

Roles of NO signaling in long-term memory formation in visual learning in an insect.

Yukihisa Matsumoto et al.

PloS one, 8(7), e68538-e68538 (2013-07-31)

Many insects exhibit excellent capability of visual learning, but the molecular and neural mechanisms are poorly understood. This is in contrast to accumulation of information on molecular and neural mechanisms of olfactory learning in insects. In olfactory learning in insects

Gastroprotective effect of diligustilide isolated from roots of Ligusticum porteri coulter & rose (Apiaceae) on ethanol-induced lesions in rats

Velazquez-Moyado J, et al.

Journal of Ethnopharmacology, 174, 403-409 (2015)

查看所有相关文献

全球贸易项目编号

货号	GTIN
D7408-5MG	04061833588512
D7408-25MG	04061832897868