E4786
艾司西酞普兰 草酸酯
≥98% (HPLC), powder, serotonin reuptake inhibitor
别名:
S-(+)-1-[3-(二甲氨基)丙基]-1-(4-氟苯基)-1,3-二氢-5-异苯并呋喃腈 草酸酯, S-(+)-西酞普兰 草酸酯
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关于此项目
经验公式（希尔记法）:
C20H21FN2O · C2H2O4
化学文摘社编号:
分子量:
414.43
UNSPSC Code:
12352200
PubChem Substance ID:
NACRES:
NA.77
MDL number:
产品名称
艾司西酞普兰 草酸酯, ≥98% (HPLC), powder
Quality Level
assay
≥98% (HPLC)
form
powder
storage condition
desiccated
color
white to tan
solubility
DMSO: ≥15 mg/mL
originator
Forest Labs
storage temp.
2-8°C
SMILES string
OC(=O)C(O)=O.CN(C)CCC[C@]1(OCc2cc(ccc12)C#N)c3ccc(F)cc3
InChI
1S/C20H21FN2O.C2H2O4/c1-23(2)11-3-10-20(17-5-7-18(21)8-6-17)19-9-4-15(13-22)12-16(19)14-24-20;3-1(4)2(5)6/h4-9,12H,3,10-11,14H2,1-2H3;(H,3,4)(H,5,6)/t20-;/m0./s1
InChI key
KTGRHKOEFSJQNS-BDQAORGHSA-N
Gene Information
human ... SLC6A4(6532)
General description
草酸右旋西酞普兰是一种抗抑郁剂。它可用于治疗惊恐性障碍和重度抑郁症(MDD)。
Application
草酸右旋西酞普兰作为一种抗抑郁剂，应用于暴露于慢性轻度应激(CMS)下的大鼠。它也用于基于闪烁亲近的热稳定分析。
Biochem/physiol Actions
右旋西酞普兰是一种选择性5-羟色胺再摄取抑制剂（SSRI）；西酞普兰的S对映体和优对映体。
草酸右旋西酞普兰是一种选择性5-羟色胺再摄取抑制剂（SSRI）；西酞普兰的S对映体和优对映体。
Features and Benefits
该化合物由Forest Labs开发。要浏览其他药物开发化合物和批准的药物/候选药物列表，单击此处。
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signalword
Warning
hcodes
Hazard Classifications
Acute Tox. 4 Dermal - Acute Tox. 4 Oral
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
商品
我们提供许多血清素受体相关产品，满足您的各类研究需求。
We offer many products related to serotonin receptors for your research needs.
André Russowsky Brunoni et al.
Sao Paulo medical journal = Revista paulista de medicina, 133(3), 252-263 (2015-07-16)
Major depressive disorder (MDD) is a common psychiatric condition, mostly treated with antidepressant drugs, which are limited due to refractoriness and adverse effects. We describe the study rationale and design of ELECT-TDCS (Escitalopram versus Electric Current Therapy for Treating Depression
Colorimetric method for the estimation of escitalopram oxalate in tablet dosage form
Vetrichelvan T, et al.
Indian Journal of Pharmaceutical Sciences, 72(2), 269-269 (2010)
Thermostabilization, expression, purification, and crystallization of the human serotonin transporter bound to S-citalopram
Coleman JA, et al.
Journal of Visualized Experiments, e54792-e54792 (2016)
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| E4786-10MG | 04061832071930 |
| E4786-50MG | 04061832071947 |