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EHU010411

MISSION® esiRNA

targeting human PGP

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NACRES:
NA.51
UNSPSC Code:
41105324
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description

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Quality Level

100

product line

MISSION®

form

lyophilized powder

esiRNA cDNA target sequence

GACCCGCACTTCAGCTACATGAAGCTCACCAAGGCCCTGCGCTACCTGCAGCAGCCCGGCTGCCTGCTCGTGGGCACCAACATGGACAACCGGCTTCCGCTTGAGAACGGCCGCTTCATCGCGGGTACCGGGTGTCTGGTCCGAGCCGTGGAGATGGCCGCCCAGCGCCAGGCCGACATCATCGGGAAGCCCAGCCGCTTCATTTTCGACTGCGTGTCCCAGGAATACGGCATCAACCCCGAGCGCACCGTCATGGTGGGAGACCGCCTGGACACAGACATCCTCCTAGGCGCCACCTGTGGCCTGAAGACCATCCTGACCCTCACCGGAGTCTCCACTCTAGGGGATGTGAAGAATAATCAGGAAAGTGACTGCGTGTCTAAGAAGAAAATGGTCCCTGACTTCTATGTTGACAGCATAGCCGACCTTTTG

Ensembl | human accession no.

ENSG00000184207

NCBI accession no.

NM_001042371

shipped in

ambient

storage temp.

−20°C

General description

MISSION® shRNA是核糖核酸内切酶制备的siRNA。它们是靶向相同mRNA序列的siRNA异质混合物。这些多重沉默触发（multiple silencing trigger）导致高度特异性的、有效的基因沉默。

如需其他详细信息并查看所有可用的esiRNA选项，请访问SigmaAldrich.com/esiRNA。

Legal Information

MISSION is a registered trademark of Merck KGaA, Darmstadt, Germany

存储类别

10 - Combustible liquids

flash_point_f

Not applicable

flash_point_c

Not applicable

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Patric J Jansson et al.
The Journal of biological chemistry, 290(15), 9588-9603 (2015-02-28)
Multidrug resistance (MDR) is a major obstacle in cancer treatment. More than half of human cancers express multidrug-resistant P-glycoprotein (Pgp), which correlates with a poor prognosis. Intriguingly, through an unknown mechanism, some drugs have greater activity in drug-resistant tumor cells

全球贸易项目编号

货号GTIN
EHU010411-20UG04061828672653
EHU010411-50UG04061828446841