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Merck
CN

F0429

氟尼辛葡甲胺

≥98% (HPLC)

别名:

2-[[2-甲基-3-(三氟甲基)苯基]氨基] -3-吡啶羧酸葡甲胺盐, 氟尼辛甲葡胺

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关于此项目

经验公式(希尔记法):
C14H11F3N2O2·C7H17NO5
化学文摘社编号:
分子量:
491.46
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
12352200
EC Number:
255-836-0
MDL number:
Assay:
≥98% (HPLC)
Form:
powder
Quality level:
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Quality Level

assay

≥98% (HPLC)

form

powder

color

white to beige

mp

136.6-137.4 °C

solubility

H2O: freely soluble

storage temp.

room temp

SMILES string

CNC[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO.Cc1c(Nc2ncccc2C(O)=O)cccc1C(F)(F)F

InChI

1S/C14H11F3N2O2.C7H17NO5/c1-8-10(14(15,16)17)5-2-6-11(8)19-12-9(13(20)21)4-3-7-18-12;1-8-2-4(10)6(12)7(13)5(11)3-9/h2-7H,1H3,(H,18,19)(H,20,21);4-13H,2-3H2,1H3/t;4-,5+,6+,7+/m.0/s1

InChI key

MGCCHNLNRBULBU-WZTVWXICSA-N

Application

氟尼辛葡甲胺已被用作电喷雾电离质谱(LC-ESI/MS)检测中的非固醇类消炎药物标准品。
氟尼辛葡甲胺(IC50 = 1 nM)可用作动物药物,用于治疗马的肠缺血、绞痛和内毒素血症。

Biochem/physiol Actions

氟尼辛葡甲胺是一种非固醇类消炎药,可阻止前列腺素合成。
COX1、COX2 和 PLA2 抑制剂非麻醉性镇痛、解热、抗炎。


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pictograms

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signalword

Warning

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

存储类别

11 - Combustible Solids

wgk

WGK 3

ppe

dust mask type N95 (US), Eyeshields, Gloves



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J Cuervo-Arango et al.
Theriogenology, 77(3), 514-524 (2011-10-01)
The development of hemorrhagic anovulatory follicles (HAF) involves luteinization and hemorrhage of the follicle. This is observed on ultrasound as an increase in the echogenicity of the granulosa layer and formation of echoic particles in the antrum. The inhibition of
E E Yeiser et al.
Journal of dairy science, 95(9), 4939-4949 (2012-08-25)
The use of flunixin meglumine (FM), a nonsteroidal antiinflammatory drug, during experimentally induced Escherichia coli mastitis was evaluated. Twenty-four primiparous and multiparous lactating dairy cows were challenged with 1×10(2) cfu of E. coli 727 in 1 uninfected quarter. Of the
J Huber et al.
Journal of dairy science, 96(1), 132-140 (2012-11-28)
Dehorning (DH) of calves is a common procedure on commercial dairy farms. Pain management of calves has been investigated in several studies. It is generally accepted that the use of local anesthesia before DH is essential for pain management. Postoperative



全球贸易项目编号

货号GTIN
F0429-100MG04061833611197
F0429-500MG04061832785424