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Merck
CN

F9381

氟米龙

≥98%

别名:

11β,17α-Dihydroxy-9-fluoro-6-methyl-1,4-pregnadiene-3,20-dione

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关于此项目

经验公式(希尔记法):
C22H29FO4
化学文摘社编号:
分子量:
376.46
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
12352212
EC Number:
207-041-5
MDL number:
Assay:
≥98%
Quality level:
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Quality Level

assay

≥98%

SMILES string

C[C@H]1C[C@H]2[C@@H]3CC[C@](O)(C(C)=O)[C@@]3(C)C[C@H](O)[C@]2(F)[C@@]4(C)C=CC(=O)C=C14

InChI

1S/C22H29FO4/c1-12-9-17-15-6-8-21(27,13(2)24)20(15,4)11-18(26)22(17,23)19(3)7-5-14(25)10-16(12)19/h5,7,10,12,15,17-18,26-27H,6,8-9,11H2,1-4H3/t12-,15-,17-,18-,19-,20-,21-,22-/m0/s1

InChI key

FAOZLTXFLGPHNG-KNAQIMQKSA-N

Gene Information

human ... NR3C1(2908)

Application


  • Topical fluorometholone treatment and desiccating stress change inflammatory protein expression in tears.: This research explores the changes in tear protein expression due to topical fluorometholone and environmental stress, offering insights into ocular surface inflammatory responses (Nättinen et al., 2018).

  • General Pharmacokinetic Model for Topically Administered Ocular Drug Dosage Forms.: This study provides a pharmacokinetic model applicable to topical ocular medications, including fluorometholone, enhancing understanding of drug dynamics in eye treatments (Deng et al., 2016).

Biochem/physiol Actions

Clinically significant in allergic conjunctivitis and as anti-inflammatory following cataract surgery.


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Hazard Classifications

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

法规信息

涉药品监管产品

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历史批次信息供参考:

分析证书(COA)

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Alejandro Portero et al.
Cornea, 32(2), 161-164 (2012-06-08)
Hairs from the caterpillar of the pine processionary moth, Thaumetopoea pityocampa, located in the pine forests of southern Europe and elsewhere, can become embedded in the cornea and conjunctiva. Disorders produced by the urticating hairs can be classified into a
Kaevalin Lekhanont et al.
Cornea, 31(2), 155-161 (2011-11-15)
To investigate the efficacy and safety of subconjunctival bevacizumab injection for the treatment of impending recurrent pterygium. A prospective, randomized, single-masked, controlled trial was conducted in 80 patients with impending recurrent pterygium. Patients were randomized into 4 groups using random
Miguel Naveiras et al.
American journal of ophthalmology, 153(5), 958-966 (2012-01-31)
To describe the incidence and causes of glaucoma after Descemet membrane endothelial keratoplasty (DMEK). Nonrandomized prospective cohort study at a tertiary referral center. The incidence of glaucoma was evaluated in the first 275 consecutive eyes that underwent DMEK for Fuchs



全球贸易项目编号

货号GTIN
F9381-100MG04061835544943
F9381-500MG04061835544950